Pleomorphic adenoma of palpebral lobe of lacrimal gland masquerading as skin adnexal tumor of eyelid
Keywords:
Lacrimal gland, Epithelialtumors, Chondroidsyringoma, Pleomorphic adenoma
Abstract
Occurrence of Lacrimal gland tumorsis rare. Benign epithelial tumors are more common of which pleomorphic adenoma is commonest. They usually occur in the orbital lobe of lacrimal gland however, they mayrarely occur in palpebral lobe. FNAC helps to rule out other pathologies and narrows the differential diagnosis. We describe a case of young female who presented with a nodular right upper eyelid swelling, clinically diagnosed as a skin-adnexal tumor. On FNAC, diagnosis of Chondroidsyringoma of skin adnexawas given. Histopathologically however it was confirmed to be Pleomorphic adenoma of lacrimal gland. Although rare, possibility of both chondroidsyringoma and pleomorphic adenoma of palpebral lobe of lacrimal gland should be considered in case of a mobile, nodular swelling in the upper eyelid. FNAC aids in diagnosis, however, histopathological examination remains the diagnostic gold standard.
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References
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11. Grossniklaus HE, Abbuhl MF, McLean IW. Immunohistologic properties of benign and malignant mixed tumor of the lacrimal gland.Am J Ophthalmol. 1990 Nov 15;110(5):540-9.
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2. Kohli M, Shah A, Bhatt S, Aggarwal S; Lacrimal gland tumors: A retrospective histopathological study. Gujarat Medical Journal, 2011; 66(1): 39-41.
3. Santos, Rodrigo Ribeiro, et al. Ten-year follow-up of a case series of primary epithelial neoplasms of the lacrimal gland: clinical features, surgical treatment and histopathological findings. Arquivosbrasileirosdeoftalmologia. Jan/Feb 2010; 73(1): 33.
4. Chandrashekhar J, Farr DR, Whear NM. Pleomorphic adenoma of Lacrimal Gland: Case report. British Journal of Oral and Maxillofacial Surgery. 2001, 39(5):390.
5. Vijaykumar A. Pleomorphic Adenoma of Lacrimal Gland in an eleven years old girl. J ClinDiagn Res. April 2013; 7(4):712–714. doi: 10.7860/JCDR/2013/4887.2889.
6. Rose GE, Wright JE.Pleomorphic adenoma of the lacrimal gland.Br J Ophthalmol. 1992 Jul;76(7):395-400. [PubMed]
7. Gupta KK, Pradhan SP, Dash AK, Mishra DB.Role of Cytology and Radiology in Diagnosis of Lacrimal Gland Pleomorphic Adenoma.Annals of Pathology and Laboratory Medicine.2016, 3(2).
8. von Holstein SL, Coupland SE, Briscoe D, Le Tourneau C, Heegaard S; Epithelial tumors of the lacrimal gland: a clinical, histopathological, surgical and oncological survey. ActaOphthalmologica, 2013; 91(3): 195-206. doi: 10.1111/j.1755-3768.2012.02402.x.
9. Weis E, Rootman J, Joly TJ, Berean KW, Al-Katan HM, Pasternak S, Bonavolontà G, Strianese D, Saeed P, Feldman KA, Vangveeravong S, Lapointe JS, White VA.Epitheliallacrimal glandtumors: pathologicclassification and current understanding. Arch Ophthalmol. 2009 Aug;127(8):1016-28. doi: 10.1001/archophthalmol.2009.209.
10. Font RL, Gamel JW. Epithelial tumors of the lacrimal gland: an analysis of 265 cases. In: Jakobiec FA, ed. Ocular and adnexal tumors. Birmingham: Aesculapius, 1978;787-805.
11. Grossniklaus HE, Abbuhl MF, McLean IW. Immunohistologic properties of benign and malignant mixed tumor of the lacrimal gland.Am J Ophthalmol. 1990 Nov 15;110(5):540-9.
12. ToopalliK,Vallury S, Pandharpurkar M. Benign Lacrimal Gland Tumors: A histopathological Study. Sch. J. App. Med. Sci., 2014; 2(6H):3396-3399. [PubMed]
13. Parks SL, Glover AT. Benign mixed tumors arising in the palpebral lobe of the lacrimal gland. Ophthalmology. 1990 Apr;97(4):526-30. [PubMed]
14. Vangveeravong S, Katz SE, Rootman J, White V. Tumors arising in the palpebral lobe of the lacrimal gland.Ophthalmology. 1996 Oct;103(10):1606-12. [PubMed]
15. Agrawal V, Gupta RL, Kumar S, Mishra K, Agarwal S. Malignant chondroidsyringoma.J Dermatol. 1998 Aug;25(8):547-9. [PubMed]
16. Nasit JG, Dhruva G. Chondroidsyringoma: a diagnosis by fine needle aspiration cytology. J CutanAesthet Surg. 2012 Jul;5(3):222-5. doi: 10.4103/0974-2077.101404. [PubMed]
17. Henderson JW. Orbital Tumors. 3rd ed. New York: RavenPress; 1994:323–342.
18. Jakobiec FA, Bilyk JR, Font RL. Lacrimal gland tumors. In: Spencer WH, ed. Ophthalmic Pathology. An Atlas and Textbook. 4th ed. Philadelphia: WB Saunders; 1996:2485–2525.
19. Mandeville JT, Roh JH, Woog JJ, Gonnering RS, Levin PS, Mazzoli RA, Ainbinder DJ, Older JJ, Moulin AP, Kiel R, Kim YD, Dryja TP.Cutaneousbenignmixedtumor (chondroidsyringoma) of the eyelid: clinicalpresentation and management. OphthalPlastReconstr Surg. 2004 Mar;20(2):110-6. [PubMed]
CITATION
DOI: 10.17511/jopm.2017.i03.13
Published: 2017-09-30
How to Cite
Dr. Sujata S Giriyan, Dr. Akanksha Agrawal, & Dr. Rajesh H Chandan. (2017). Pleomorphic adenoma of palpebral lobe of lacrimal gland masquerading as skin adnexal tumor of eyelid. Tropical Journal of Pathology and Microbiology, 3(3), 305-308. https://doi.org/10.17511/jopm.2017.i03.13
Section
Case Report
OAI - Open Archives Initiative
