Role of The Bethesda system for reporting fine needle aspiration cytology of lesions of thyroid and it’s histopathological correlation

2022-12-08T09:10:38+00:00

The incidence of clinically apparent thyroid swellings in the general population is 4–5%. Majority of these swellings are benign in nature, among which goiter being most common. The prevalence of goiter is more than 40 million in India with more than 2 billion globally. The Bethesda system is a uniform reporting system for thyroid cytology that facilitates the clarity of communication among cytopathologists, radiologists, and surgeons and facilitates cytohistologic correlation for thyroid diseases. METHODS: This is a retrospective review done by retrieving the records (cytology and histopathology) of 50 patients who have undergone FNAC of thyroid from the archives of Department of Pathology over a period of 1.5 years and the results were analyzed using descriptive statistics and Chi square test with Software SPSS version 23.

RESULTS: Based on the Bethesda system of classification of thyroid lesions, out of 44 satisfactory samples; 33 lesions were diagnosed as benign (Group 2), 1 was in category of suspicious for follicular neoplasm(group 4), 2 were diagnosed as suspicious for malignancy (Group 5), and 8 cases were malignant (Group 6). In the present study, the sensitivity of FNAC was 100%, specificity 83%.

CONCLUSION: Reviewing the thyroid FNAs with the Bethesda system for reporting allowed precise cytological diagnosis. It represents standardization and reproducibility in reporting thyroid cytology with improved clinical significance and greater predictive value. Nature of the disease, experience of cytopathologist, and understanding of certain limitations determine its diagnostic utility.

Keywords: Cytohistologic correlation, Fine‑needle aspiration, thyroid lesion, Thyroid, The Bethesda system,

The Histopathological study of lesions of nasal cavity, paranasal sinuses and nasopharynx in Eastern UP(India)

2023-03-09T11:52:40+00:00

ABSTRACT-

BACKGROUND

Masses in the nasal cavity, paranasal sinuses and nasopharynx a hetergenous group of lesions with a broad spectrum of histopathology features,So careful histological workup is essential for a correct diagnosis and to determine extent of involvement and prompt treatment.

The present study has been conducted on 158 cases in the department of pathology, BRD Medical college , Gorakhpur.

AIMS AND OBJECTIVE

(1)To establish histopathological diagnosis of Inflammatory, benign and malignant lesions of nasal cavity, paranasal sinuses and nasopharynx

(2) To categorize these lesions into non- neoplstic and neoplastic lesions and to study their histopathological patterns.

(3) To compare findings of our study with other studies.

MATERIAL AND METHOD

This was a prospective study of sinonasal lesions those were biopsied or surgically excised and received in pathology department.

RESULT

A total of 158 cases of nasal , paranasal lesions were reported during the study period.

Out of total 158 cases, 135 cases were inflammatory and non-neoplastic lesions,20 cases were benign and 03 cases were malignant lesions.Age ranged from 08 yrs to 78 yrs with male predominance and majority cases belonged to Hindu community.

Out of 135 inflammatory or non neoplastic cases most common lesion was nasal polyp and among 20 benign cases, Inverted papilloma was the commonest lesion.

Out of 03 malignant lesion, Squamous cell carcinoma was the predominant histological type of lesion.

CONCLUSION- Nasal, Paranasal and Nasopharyngeal lesions comprises of wide spectrum of lesions but their clinical manifestations are very limited.Hence a careful histopathological examination is mandatory for proper diagnosis so that a correct and timely intervention can be made.

In this study we concluded that in Eastern UP, malignant lesions of nasal , paranasal and nasopharyngeal regions are very less in comparison to inflammatory and benign cases.

Tropical Journal of Pathology and Microbiology

Role of The Bethesda system for reporting fine needle aspiration cytology of lesions of thyroid and it’s histopathological correlation

The Histopathological study of lesions of nasal cavity, paranasal sinuses and nasopharynx in Eastern UP(India)