Observational study on clinicopathological profile of thrombocytopenia cases in a medical college hospital

  • Dr. Ajay Kumar Associate Professor, Department of Pathology, Mata Gujri Memorial Medical College and Lions Seva Kendra Hospital, Kishanganj, Bihar
  • Dr. Avinash Priyadarshi Assistant Professor, Department of Pathology, Mata Gujri Memorial Medical College and Lions Seva Kendra Hospital, Kishanganj, Bihar
  • Dr. Sanjay Kumar Professor, Department of Pathology, Mata Gujri Memorial Medical College and Lions Seva Kendra Hospital, Kishanganj, Bihar
  • Dr. Prabhat Kumar Lal Associate Professor, Department of PSM, Darbhanga Medical College, Darbhanga, Bihar, India
Keywords: Observational Study, Platelet Count, Thrombocytopenia

Abstract

Introduction: Thrombocytopenia is a commonly encountered condition with varying aetiologies ranging from infective to chronic conditions and malignancies. Knowledge of causes and pattern of disease is helpful in management of cases.

Aims & objectives: The present study was conducted to assess the causes, clinical profile and findings of laboratory investigations of patients suffering from thrombocytopenia.

Material & Methods: The present cross-sectional hospital-based study was conducted upon 99 patients suffering from thrombocytopenia. Detailed clinical history, physical examination and reports of laboratory investigations were noted.

Results: 34.3% patients belonged to the age group of 21-30 years. 57.6% of them were males. Thrombocytopenia was mild (1,00,000-1,50,000) in 24.2% patients, moderate (50,000-1,00,000) in 52.5% and severe (<50,000) in 23.2%. Dengue accounted for 31.3% cases, malaria for 16.2%, enteric fever for 7.1% and septicaemia for 3%. Megaloblastic anaemia was responsible in 24.2% cases. Most common site for bleeding was skin and mucous membrane where bleeding manifested in the form of petechiae, purpura and ecchymosis (18.2%).

Conclusion: Knowledge of causes and pattern of disease is helpful in management of cases.

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CITATION
DOI: 10.17511/jopm.2019.i09.13
Published: 2019-09-30
How to Cite
Kumar, A., Priyadarshi, A., Kumar, S., & Kumar Lal, P. (2019). Observational study on clinicopathological profile of thrombocytopenia cases in a medical college hospital. Tropical Journal of Pathology and Microbiology, 5(9), 696-702. https://doi.org/10.17511/jopm.2019.i09.13
Section
Original Article