Study of endometrial lesions in patients presenting with abnormal uterine bleeding to a Medical College Hospital
Keywords:
Abnormal Uterine Bleeding, Endometrial lesions, Histopathology, Cross-sectional study
Abstract
Introduction: Abnormal uterine bleeding is common presentation in gynaecological OPD. Endometrial biopsy is helpful in proper diagnosis and ruling out malignancy.
Methods: The present study was cross-sectional in nature conducted upon 164 endometrial specimens of patients suffering from abnormal uterine bleeding to assess the histopathological profile. Profile of patients, symptoms and histopathological findings were noted.
Results: 41-50 years was the most common age group (32.9 %). Most common bleeding pattern observed was menorrhagia (26.8%) followed by metrorrhagia (25%). The most common histopathological finding was proliferative phase (25.6%) followed by secretory phase (22.6%). Polyp was present in 7.3% cases and endometrial carcinoma was observed in 2.4% cases.
Conclusion: Histopathological assessment of endometrial specimen is helpful in diagnosis in these cases.
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References
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10. Cornitescu F, Tanase F, Simionescu C, Illiescu D. Clinical, histopathological and therapeutic considerations in non-neoplastic abnormal uterine bleeding in menopause transition. Rom J Morphol Embryol. 2011;52(3):759-765.
11. Singh S, Pandey P, Agarwal S, Kaur S, Singh S. Spectrum of uterine lesions presenting as abnormal uterine bleeding in a rural north Indian population: a study from tertiary care center. Int J Res Med Sci. 2016;4(8):3250-3254. http://dx.doi.org/10.18203/2320-6012.ijrms20162274.
12. Parmar J, Desai D. Study of endometrial pathology in abnormal uterine bleeding. Int J Reprod Contracept Obstet Gynecol. 2013;2(2):182-185. doi: 10.5455/2320-1770.ijrcog20130614.
13. Shajitha S., Sangeereni M, Mallika A. Study of endometrial pathology in abnormal uterine bleeding. In J Curr Med Sci. 2017;7(10):324-326. doi: http://dx.doi.org/10.24327/ijcmes2017.07100025.
14. Saraswathi D, Thanka J, Shalinee R, Aarthi R, Jaya V, Kumar PV. Study of Endometrial Pathology in Abnormal Uterine Bleeding. J Obstet Gynecol India. 2011;61(4):426–443. doi 10.1007/s13224-011-0047-2.
2. Munro MG, Critchley HO, Broder MS, et al. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet. 2011;113 (1):3-13. doi: 10.1016/j.ijgo. 2010.11. 011. Epub 2011 Feb 22.
3. Padubidri VG, Daftary SN. Howkins and Bourne Shaw's textbook of gynaecology.16th ed. Elsevier;2015:321-322.
4. Moodley M, Roberts C. Clinical pathway for the evaluation of postmenopausal bleeding with an emphasis on endometrial cancer detection. J Obstet Gynaecol. 2004;24 (7):736-741. doi: https://doi.org/10.1080/014436104100009394
5. Goodman A. Abnormal genital tract bleeding. Clin Cornerstone. 2000;3(1):25-35. doi: https://doi.org/10.1016/S1098-3597(00)90019-X
6. Khare A, Bansal R, Sharma P, Ehlence N. Morphological spectrum of endometrium in patients presenting with dysfunctional uterine bleeding. People’s J Res. 2012;5(2):13-16.
7. Ely JW, Kennedy CM, Clark EC, Bowdler NC. Abnormal Uterine Bleeding: A Management Algorithm. J Am Board Fam Med. 2006;19(6):590–602. doi: https://doi.org/10.3122/jabfm.19.6.590
8. Litta P, Merlin F, Saccardi C, Pozzan C, Sacco G, Fracas M et al. Role of hysteroscopy with endometrial biopsy to rule out endometrial cancer in postmenopausal women with abnormal uterine bleeding. Maturitas 2005; 50(2):117-123. doi: https://doi.org/10.1016/j.maturitas.2004.05.003
9. Iqbal MB, Kambale T, Khandelwal A, Koshy A, Banerjee B. Spectrum of Endometrial lesions in patients presenting with abnormal uterine bleeding. Indian J Pathol Oncol. 2018;5(4):587-591. doi: 10.18231/2394-6792.2018.0113.
10. Cornitescu F, Tanase F, Simionescu C, Illiescu D. Clinical, histopathological and therapeutic considerations in non-neoplastic abnormal uterine bleeding in menopause transition. Rom J Morphol Embryol. 2011;52(3):759-765.
11. Singh S, Pandey P, Agarwal S, Kaur S, Singh S. Spectrum of uterine lesions presenting as abnormal uterine bleeding in a rural north Indian population: a study from tertiary care center. Int J Res Med Sci. 2016;4(8):3250-3254. http://dx.doi.org/10.18203/2320-6012.ijrms20162274.
12. Parmar J, Desai D. Study of endometrial pathology in abnormal uterine bleeding. Int J Reprod Contracept Obstet Gynecol. 2013;2(2):182-185. doi: 10.5455/2320-1770.ijrcog20130614.
13. Shajitha S., Sangeereni M, Mallika A. Study of endometrial pathology in abnormal uterine bleeding. In J Curr Med Sci. 2017;7(10):324-326. doi: http://dx.doi.org/10.24327/ijcmes2017.07100025.
14. Saraswathi D, Thanka J, Shalinee R, Aarthi R, Jaya V, Kumar PV. Study of Endometrial Pathology in Abnormal Uterine Bleeding. J Obstet Gynecol India. 2011;61(4):426–443. doi 10.1007/s13224-011-0047-2.
CITATION
DOI: 10.17511/jopm.2019.i09.09
Published: 2019-09-30
How to Cite
Ranjan Bhowmik, S., Singh, R., & Kumar Lal, P. (2019). Study of endometrial lesions in patients presenting with abnormal uterine bleeding to a Medical College Hospital. Tropical Journal of Pathology and Microbiology, 5(9), 673-677. https://doi.org/10.17511/jopm.2019.i09.09
Section
Original Article
OAI - Open Archives Initiative
