Primary Omental Leiomyosarcoma: A Rare Case Report
Keywords:
Extra-gastrointestinal stromal tumor, Leiomyosarcoma, Omentum
Abstract
Primary leiomyosarcoma of greater omentum is rare and mimics gastrointestinal stromal tumor (GIST) due to their common origin. A 65 years old male presented with a large mass per abdomen of one year duration. Imaging findings were suggestive of extra-gastrointestinal stromal tumor (E-GIST) arising from greater omentum. The mass was excised. On microscopy, the diagnosis of leiomyosarcoma and E-GIST were considered. The tumor cells showed immunoreactivity for smooth muscle actin, muscle-specific actin, heavy-caldesmon and desmin and were immunonegative for CD117, DOG1 and CD34, hence confirming primary leiomyosarcoma of greater omentum. We present this case for its rarity.
Downloads
Download data is not yet available.
References
1. Joe DH, Yang JM, Kim HS, Kim SS, Choi SW, Choi SH, et al. A case of primary leiomyosarcoma of the lesser omentum. Korean J Intern Med 1999;14(1):88-90. doi: 10.3904/kjim.1999.14.1.88. [PubMed]
2. Branes A, Bustamante C, Valbuena J, Pimentel F, Quezada N. Primary leiomyosarcoma of the greater omentum: a case report. Int J Surg Case Rep. 2016;28:317-320. doi: 10.1016/j.ijscr.2016.10.025. Epub 2016 Oct 14. [PubMed]
3. Barel O, Qian C, Manolitsas T. Primary leiomyosarcoma of the omentum presenting as an ovarian carcinoma, case report and review of the literature. Gynecologic oncology reports 2016;17:75-8. doi: 10.1016/j.gore.2016.07.002.
4. Yang TH, Hwang JI, Hung SW, Wang RC, Lee T, Tyan YS. Gastrointestinal stromal tumor of the omentum and mesentry mimicking peritoneal carcinomatosis: a case report. Chin J Radiol 2006;31:53-8.
5. Lee BN, Ouh YT, Choi HJ, Yang SY, Lee JK, Hong JH. Leiomyosarcoma of the ovary mimicking gastrointestinal stromal tumor originating from small bowel: A case report and literature review. Gynecol Obstet 2016;6(2):359. doi: 10.4172/2161-0932.1000359.
6. Chu CY, Wong MF, Leung KC, Tsui P, Chau WK. Primary omental leiomyosarcoma: Unusual manifestation of a rare entity. Hong Kong J Radiol 2012;15(2):113-8.
7. Fagkrezoz D, Touloumis Z, Giannila M, Penlidis C, Papaparaskeva K, Triantopoulou C. Extra-gastrointestinal stromal tumor of the omentum: a rare case report and review of literature. Rare tumors 2012;4(3):141-4. doi:10.4081/rt.2012.e44. [PubMed]
8. Miettinen M. Smooth muscle tumors of soft tissue and non-uterine viscera: biology and prognosis. Modern Pathology 2014;27(1):17-29. doi:10.1038/modpathol.2013.178. [PubMed]
2. Branes A, Bustamante C, Valbuena J, Pimentel F, Quezada N. Primary leiomyosarcoma of the greater omentum: a case report. Int J Surg Case Rep. 2016;28:317-320. doi: 10.1016/j.ijscr.2016.10.025. Epub 2016 Oct 14. [PubMed]
3. Barel O, Qian C, Manolitsas T. Primary leiomyosarcoma of the omentum presenting as an ovarian carcinoma, case report and review of the literature. Gynecologic oncology reports 2016;17:75-8. doi: 10.1016/j.gore.2016.07.002.
4. Yang TH, Hwang JI, Hung SW, Wang RC, Lee T, Tyan YS. Gastrointestinal stromal tumor of the omentum and mesentry mimicking peritoneal carcinomatosis: a case report. Chin J Radiol 2006;31:53-8.
5. Lee BN, Ouh YT, Choi HJ, Yang SY, Lee JK, Hong JH. Leiomyosarcoma of the ovary mimicking gastrointestinal stromal tumor originating from small bowel: A case report and literature review. Gynecol Obstet 2016;6(2):359. doi: 10.4172/2161-0932.1000359.
6. Chu CY, Wong MF, Leung KC, Tsui P, Chau WK. Primary omental leiomyosarcoma: Unusual manifestation of a rare entity. Hong Kong J Radiol 2012;15(2):113-8.
7. Fagkrezoz D, Touloumis Z, Giannila M, Penlidis C, Papaparaskeva K, Triantopoulou C. Extra-gastrointestinal stromal tumor of the omentum: a rare case report and review of literature. Rare tumors 2012;4(3):141-4. doi:10.4081/rt.2012.e44. [PubMed]
8. Miettinen M. Smooth muscle tumors of soft tissue and non-uterine viscera: biology and prognosis. Modern Pathology 2014;27(1):17-29. doi:10.1038/modpathol.2013.178. [PubMed]
CITATION
DOI: 10.17511/jopm.2017.i02.09
Published: 2017-06-30
How to Cite
Dr Bhumika J Bhandari, Dr Meena N Jadhav, Dr Rashmi K Patil, & Dr Shreekant K Kittur. (2017). Primary Omental Leiomyosarcoma: A Rare Case Report. Tropical Journal of Pathology and Microbiology, 3(2), 128-131. https://doi.org/10.17511/jopm.2017.i02.09
Section
Case Report
OAI - Open Archives Initiative
