Primary squamous cell carcinoma of breast: A Rare Case Report
Keywords:
Breast, Metaplastic, Squamous cell carcinoma, Triple negative
Abstract
Primary squamous cell carcinoma (SCC) of breast is a pure epithelial type of metaplastic carcinoma accounting for less than 0.1% of all breast cancers. A 70 year female presented with left breast lump of 4 months duration. Toilet mastectomy was done. Histopathology proved it to be primary SCC (large cell keratinizing) of breast. On immunohistochemistry, tumor cells were positive for pancytokeratin and epidermal growth factor receptor and negative for estrogen, progesterone receptors and HER-2/neu (triple negative). On follow up, after 1 month, patient presented with recurrence and metastasis to ipsilateral axillary lymph nodes. This case is presented for its rarity.
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References
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2. Vekariya M, Gupta V, Pednekar A, Nagur B, Mahna A, Patankar R. Primary squamous cell carcinoma of the breast: A rare case report. Int J Sci Stud 2014;2(8):226-8.
3. Dasgupta S, Dasgupta J, Sarkar R. Primary Squamous Cell Carcinoma of Breast: A Case Report with Brief Review of Literature. Sch J Med Case Rep 2014; 2(7):457-60.
4. Flikweert ER, Hofstee M, Liem MS. Squamous cell carcinoma of the breast: a case report. World J Surg Oncol. 2008 Dec 21;6:135. doi: 10.1186/1477-7819-6-135. [PubMed]
5. Mitra B, Pal M, Debnath S, Paul B, Saha TN, Maiti A. Primary squamous cell carcinoma of breast with ipsilateral axillary lymph node metastasis: An unusual case. Int J Surg Case Rep. 2011;2(7):194-7. doi: 10.1016/j.ijscr.2011.06.006. Epub 2011 Jun 25. [PubMed]
6. Gursel B, Bayrak IK, Cakir S, Yildiz L, Gursel M, Yucel I. Primary squamous cell carcinoma of the breast: A case report and review of the literature. Turkish journal of cancer 2007;37(3):114-6.
7. Carbone S, Lobo Alvarez R, Lamacchia A, Almenar Gil A, Martin Hernandez R, Lopez Guerra JL, Marsiglia H. Primary squamous cell carcinoma of the breast: A rare case report. Rep Pract Oncol Radiother. 2012 Aug 9;17(6):363-6. doi: 10.1016/j.rpor.2012.07.004. eCollection 2012.
8. Karamouzis MV, Fida A, Apostolikas N, Rigatos G. A case of HER-2(+) squamous cell breast carcinoma: an unusual presentation of an unusual clinical entity. Eur J Surg Oncol. 2006 Dec;32(10):1250-1. Epub 2006 Jun 21. [PubMed]
9. Bhosale SJ, Kshirsagar AY, Deshmukh SJ, Jagtap SV, Langade YB. Squamous cell carcinoma of the breast. Am J Case Rep 2013:14:188-90. doi:10.12659/AJCR.883934. [PubMed]
CITATION
DOI: 10.17511/jopm.2017.i02.07
How to Cite
Dr Rekha M. Haravi, Dr. Bhumika J. Bhandari, Dr Shreekant K. Kittur, & Dr Sabu N. Satihal. (1). Primary squamous cell carcinoma of breast: A Rare Case Report. Tropical Journal of Pathology and Microbiology, 3(2), 120-123. https://doi.org/10.17511/jopm.2017.i02.07
Section
Case Report
OAI - Open Archives Initiative
