Role of The Bethesda system for reporting fine needle aspiration cytology of lesions of thyroid and it’s histopathological correlation

  • ROSE MATHEW CHERKOTTU yenepoya medical college
  • Krishnaraj Upadhyaya Professor, Department of pathology
  • Shubha Sudhakar
Keywords: Cytohistologic correlation, Fine needle aspiration, thyroid lesion, Thyroid, The Bethesda system

Abstract

The incidence of clinically apparent thyroid swellings in the general population is 4–5%. Majority of these swellings are benign in nature, among which goiter being most common. The prevalence of goiter is more than 40 million in India with more than 2 billion globally. The Bethesda system is a uniform reporting system for thyroid cytology that facilitates the clarity of communication among cytopathologists, radiologists, and surgeons and facilitates cytohistologic correlation for thyroid diseases. METHODS: This is a retrospective review done by retrieving the records (cytology and histopathology) of 50 patients who have undergone FNAC of thyroid from the archives of Department of Pathology over a period of 1.5 years and the results were analyzed using descriptive statistics and Chi square test with Software SPSS version 23.

RESULTS: Based on the Bethesda system of classification of thyroid lesions, out of 44 satisfactory samples; 33 lesions were diagnosed as benign (Group 2), 1 was in category of suspicious for follicular neoplasm(group 4), 2 were diagnosed as suspicious for malignancy (Group 5), and 8 cases were malignant (Group 6). In the present study, the sensitivity of FNAC was 100%, specificity 83%.

CONCLUSION: Reviewing the thyroid FNAs with the Bethesda system for reporting allowed precise cytological diagnosis. It represents standardization and reproducibility in reporting thyroid cytology with improved clinical significance and greater predictive value. Nature of the disease, experience of cytopathologist, and understanding of certain limitations determine its diagnostic utility.

Keywords: Cytohistologic correlation, Fine‑needle aspiration, thyroid lesion, Thyroid, The Bethesda system,

Downloads

Download data is not yet available.

Author Biographies

Krishnaraj Upadhyaya, Professor, Department of pathology

MD,Professor, Department of pathology

Shubha Sudhakar

MD, Department of pathology

References

1. Nandedkar SS, Dixit M, Malukani K, Varma AV, Gambhir S. Evaluation of thyroid lesions by fine-needle aspiration cytology according to Bethesda system and its histopathological correlation. International Journal of Applied and Basic Medical Research. 2018 Apr;8(2):76.
2. Key Statistics for Thyroid Cancer.American cancer society.https://www.cancer.org/cancer/thyroid-cancer/about/key-statistics.html.January8,2020
3. Kulkarni CV, Mittal M, Nema M, Verma R. Diagnostic role of the Bethesda System for Reporting Thyroid Cytopathology in an academic institute of Central India: one year experience. Indian J Basic Appl Med Res. 2016;5:157-66.
4. Cibas ES, Ali SZ. The 2017 Bethesda system for reporting thyroid cytopathology. Thyroid. 2017 Nov 1;27(11):1341-6.
5. Garg S, Desai NJ, Mehta D, Vaishnav M. To establish Bethesda system for diagnosis of thyroid nodules on the basis of FNAC with histopathological correlation. Journal of clinical and diagnostic research: JCDR. 2015 Dec;9(12):EC17.
6 Ugurluoglu C, Dobur F, Karabagli P, Celik ZE. Fine needle aspiration biopsy of thyroid nodules: cytologic and histopathologic correlation of 1096 patients. International journal of clinical and experimental pathology. 2015;8(11):14800.
7. Agrawal D, Bhake AS, Rastogi N, Laishram S, Wankhade A, Agarwal A. Role of Bethesda system for reporting thyroid lesion and its correlation with histopathological diagnosis. Journal of Datta Meghe Institute of Medical Sciences University. 2019 Apr 1;14(2):74..
8. Naz S, Hashmi AA, Faridi N, Edhi MM, Kamal A, Khan M. Diagnostic accuracy of Bethesda system for reporting thyroid cytopathology: an institutional perspective. International archives of medicine. 2014 Dec 1;7(1):46.
9. Anand B, Ramdas A, Ambroise MM, Kumar NP. The Bethesda System for Reporting Thyroid Cytopathology: A Cytohistological Study. Journal of Thyroid Research. 2020;2020.
10. . Yassa L, Cibas ES, Benson CB, Frates MC, Doubilet PM, Gawande AA, et al. Long term assessment of a multidisciplinary approach to thyroid nodule diagnostic evaluation. Cancer 2007;111:508 16.
11. Nayar R, Ivanovic M. The indeterminate thyroid fine needle aspiration: Experience from an academic center using terminology similar to that proposed in the 2007 national cancer institute thyroid fine needle aspiration state of the science conference. Cancer 2009;117:195 202.
12. Jo VY, Stelow EB, Dustin SM, Hanley KZ. Malignancy risk for fine needle aspiration of thyroid lesions according to the Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol 2010;134:450 6.
How to Cite
CHERKOTTU, R. M., Upadhyaya, K., & Sudhakar, S. (2022). Role of The Bethesda system for reporting fine needle aspiration cytology of lesions of thyroid and it’s histopathological correlation. Tropical Journal of Pathology and Microbiology, 8(5), 60-64. Retrieved from https://pathology.medresearch.in/index.php/jopm/article/view/614
Section
Original Article