Unravelling the mystery behind an unusual case of Portal Hypertension

  • Rasmi Unnikrishnan Senior Registrar, Department of Pathology, Lakeshore Hospital and Research Centre, Ernakulam, Kerala, India
  • Dr. Mathew Philip HOD - Senior Consultant, Department of Gastroenterology, Lisie hospital, Ernakulam, Kerala, India
  • Senior Consultant, Lead Liver transplant surgeon, Lakeshore Hospital and Research Centre, Ernakulam, Kerala, India
  • Pushpa Mahadevan HOD - Senior consultant, Department of Pathology, Lakeshore Hospital and Research Centre, Ernakulam, Kerala,India
Keywords: Portal hypertension, Arsenic poisoning, Hepatoportal sclerosis, Angiosarcoma

Abstract

A 38yr old male was incidentally detected to have chronic liver disease with portal hypertension. Hegives a family history of liver disease. On complete workup, the arsenic levels in his family memberswere found to be high. His liver biopsy showed features of Hepatoportal sclerosis. Two years later,his liver imaging showed a suspicious nodule in the Right lobe, following which he underwent a livedonor liver transplant. Histopathology of the explanted liver revealed, areas of cavernoushemangioma, epithelioid hemangioendothelioma with a focus of diffusely infiltrating Angiosarcoma,in a background of Hepatoportal sclerosis.

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How to Cite
Rasmi Unnikrishnan, Mathew Philip, Abhishek Yadav, & Pushpa Mahadevan. (2022). Unravelling the mystery behind an unusual case of Portal Hypertension. Tropical Journal of Pathology and Microbiology, 8(2), 47-51. Retrieved from https://pathology.medresearch.in/index.php/jopm/article/view/600
Section
Case Report