Diagnosis of Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease) by Fine Needle Aspiration Cytology in a Paediatric patient

  • Dr. Neema Ankur Rana Assistant Professor, Department of Pathology, Baroda Medical College, Vadodara, Gujarat, India
  • Dr. Durva Vijaykumar Patel Third-year Resident, Department of Pathology, Baroda Medical College, Vadodara, Gujarat, India
  • Dr. Hiral Samir Shah Tutor, Department of Pathology, Baroda Medical College, Vadodara, Gujarat, India
  • Dr. Meena Rajiv Daveshwar Associate Professor, Department of Pathology, Baroda Medical College, Vadodara, Gujarat, India
Keywords: Rosai-Dorfman Disease, Lymphadenopathy, Emperipolesis

Abstract

Rosai-Dorfman Disease (RDD) is also known as Sinus Histiocytosis of Massive Lymphadenopathy (SHML). Clinically Rosai-Dorfman Disease is characterized by massive, painless, bilateral cervical lymph node enlargement, often mimics lymphoma. Microscopically, it shows dilatation of lymphatic sinuses occupied by numerous lymphocytes and proliferation of histiocytes with abundant pale eosinophilic cytoplasm containing engulfed lymphocytes or plasma cells- emperipolesis.

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References

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CITATION
DOI: 10.17511/jopm.2021.i04.10
Published: 2021-08-31
How to Cite
Dr. Neema Ankur Rana, Dr. Durva Vijaykumar Patel, Dr. Hiral Samir Shah, & Dr. Meena Rajiv Daveshwar. (2021). Diagnosis of Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease) by Fine Needle Aspiration Cytology in a Paediatric patient. Tropical Journal of Pathology and Microbiology, 7(4), 215-218. https://doi.org/10.17511/jopm.2021.i04.10
Section
Case Report