Microfilaria in fine needle aspiration smears of neoplastic lesions: a case series
Keywords:
Microfilaria, Non Hodgkin lymphoma, Fine Needle Aspiration Cytology
Abstract
Filariasis is a major public health problem in south East Asia including India. It is transmitted by bite of culex mosquito and most commonly caused by Wauchereria bancrofti. Conventional mode of diagnosis is demonstration of microfilaria in peripheral blood smear and body fluid. Co-existence of microfilaria with neoplastic lesions are rare. We present herewith 5 interesting cases of neoplastic lesions where microfilaria were coexistent with one case each of non Hodgkin lymphoma, metastatic adenocarcinoma of supraclavicular lymph node, metastatic adenocarcinoma of cervical lymph node, Infiltrating ductal carcinoma of breast, benign phylloides tumor of breast.
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References
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9. Kapila K, Verma K. Diagnosis of parasites in fine needle breast aspirates. Acta Cytol. 1996 Jul-Aug;40(4):653-6. [PubMed]
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13. Pandit AA, Shah RK, Shenoy SG. Adult filarial worm in a fine needle aspirate of a soft tissue swelling. Acta Cytol. 1997 May-Jun;41(3):944-6. [PubMed]
14. Sharma S, Rawat A, Chowhan A. Microfilaria in bone marrow aspiration smears, correlation with marrow hypoplasia: a report of six cases. Indian J Pathol Microbiol 2006; 49(4): 566-8. [PubMed]
15. Aron M, Kapila K, Sarkar C, Verma K. Microfilariae of Wuchereria bancrofti in cyst fluid of tumors of the brain: a report of three cases. Diagn Cytopathol. 2002 Mar;26(3):158-62. [PubMed]
16. Avasthi R, Jain AP, Swaroop K, Samal N. bancroftian microfilariasis in association wih pulmonary tuberculosis. Report of a case with diagnosis by fine needle aspiration. Acta Cytol 1991; 35(6): 717-8.
17. Marathe A, Handa V, Mehta GR, Mehta A, Shah PR. Early diagnosis of filarial pleural effusion. Indian J Med Microbiol. 2003 Jul-Sep;21(3):207-8. [PubMed]
18. Charan A, Sinha K. Constrictive pericarditis following filarial effusion. Indian Heart J. 1973 Jul;25(3):213-5.
19. Mehrotra R, Gupta OP, Gupta RK. Filarial ascites clinically mimicking malignancy. Acta Cytol. 1996 Nov-Dec;40(6):1329-30. [PubMed]
20. Vassenwala SM, Khan AA. Microfilaria in urinary sediment smears in association with carcinoma of urinary bladder.Report of two cases with review of literature. J Cytol 1990; 7:19-21.
21. Walter A, Krishnaswami H, Cariappa A. Microfilariae of Wuchereria bancrofti in cytologic smears. Acta Cytol. 1983 Jul-Aug;27(4):432-6. [PubMed]
22. Atal P, Choudhury M, Ashok S. Coexistence of carcinoma of the breast with microfilariasis. Diagn Cytopathol. 2000 Apr;22(4):259-60. [PubMed]
23. Kolte SS, Satarkar RN,Mane PM. Microfilaria concomitant with metastatic deposits of adenocarcinoma in lymph node fine needle aspiration cytology: A chance finding. J Cytol. 2010 Apr; 27(2): 78–80.
24. Agarwal PK, Srivastava AN, Agarwal N. Microfialria in association with neoplasms. A report of six cases. Acta Cytol 1982; 26: 480-90.
2. Park K. Epidemiology of Communicable Diseases. In Park JE, Park K, (Eds): Textbook of Preventive and Social Medicine, 20th ed., Jabalpur, Banarasidas Bhanot, 2005,199-204.
3. Meyers WM, Neafi RC, Connor DH. Edited by Binford C.H.,Connor D.H. Diseases caused by filarial Nematodes-Bancroftian and Malayan Filariasis Pathology of Tropical and Extraordinary diseases. An Atlas. Vol II. Washington D.C:Armed Forces Institute of Pathology; 1976. p. 340-55.
4. Melrose WD. Lymphatic filariasis: new insights into an old disease. Int J Parasitol. 2002 Jul;32(8):947-60. [PubMed]
5. Gupta S, Sodhani P, Jain S, Kumar N. Microfilariae in association with neoplastic lesions: report of five cases. Cytopathology. 2001 Apr;12(2):120-6. [PubMed]
6. Varghese R, Raghuveer CV, Pai MR, Bansal R. Microfilariae in cytologic smears: a report of six cases. Acta Cytol. 1996 Mar-Apr;40(2):299-301. [PubMed]
7. Gangopadhyay M, Biswas B, Chowdhury M, Deoghoria D. Microfilaria in thyroid aspirate - An unexpected finding. J Cytol. 2011 Oct;28(4):240-1. doi: 10.4103/0970-9371.86366. [PubMed]
8. Agarwal R, Khanna D, Barthwal SP. Microfilariae in a cytologic smear from cavernous hemangioma of the liver. A case report. Acta Cytol. 1998 May-Jun;42(3):781-2. [PubMed]
9. Kapila K, Verma K. Diagnosis of parasites in fine needle breast aspirates. Acta Cytol. 1996 Jul-Aug;40(4):653-6. [PubMed]
10. Sah SP, Rani S, Mahto R. Microfilariae in lymph node aspirates. Acta Cytol. 2002 Jan-Feb;46(1):73-5. [PubMed]
11. Pandit A, Prayag AS. Microfilaria in a thyroid aspirate smear: an unusual finding. Acta Cytol. 1993 Sep-Oct;37(5):845-60. [PubMed]
12. Sahu KK, Pai P, Raghuveer CV, Pai RR. Microfilaria in a fine needle aspirate from the salivary gland. Acta Cytol. 1997 May-Jun;41(3):954. [PubMed]
13. Pandit AA, Shah RK, Shenoy SG. Adult filarial worm in a fine needle aspirate of a soft tissue swelling. Acta Cytol. 1997 May-Jun;41(3):944-6. [PubMed]
14. Sharma S, Rawat A, Chowhan A. Microfilaria in bone marrow aspiration smears, correlation with marrow hypoplasia: a report of six cases. Indian J Pathol Microbiol 2006; 49(4): 566-8. [PubMed]
15. Aron M, Kapila K, Sarkar C, Verma K. Microfilariae of Wuchereria bancrofti in cyst fluid of tumors of the brain: a report of three cases. Diagn Cytopathol. 2002 Mar;26(3):158-62. [PubMed]
16. Avasthi R, Jain AP, Swaroop K, Samal N. bancroftian microfilariasis in association wih pulmonary tuberculosis. Report of a case with diagnosis by fine needle aspiration. Acta Cytol 1991; 35(6): 717-8.
17. Marathe A, Handa V, Mehta GR, Mehta A, Shah PR. Early diagnosis of filarial pleural effusion. Indian J Med Microbiol. 2003 Jul-Sep;21(3):207-8. [PubMed]
18. Charan A, Sinha K. Constrictive pericarditis following filarial effusion. Indian Heart J. 1973 Jul;25(3):213-5.
19. Mehrotra R, Gupta OP, Gupta RK. Filarial ascites clinically mimicking malignancy. Acta Cytol. 1996 Nov-Dec;40(6):1329-30. [PubMed]
20. Vassenwala SM, Khan AA. Microfilaria in urinary sediment smears in association with carcinoma of urinary bladder.Report of two cases with review of literature. J Cytol 1990; 7:19-21.
21. Walter A, Krishnaswami H, Cariappa A. Microfilariae of Wuchereria bancrofti in cytologic smears. Acta Cytol. 1983 Jul-Aug;27(4):432-6. [PubMed]
22. Atal P, Choudhury M, Ashok S. Coexistence of carcinoma of the breast with microfilariasis. Diagn Cytopathol. 2000 Apr;22(4):259-60. [PubMed]
23. Kolte SS, Satarkar RN,Mane PM. Microfilaria concomitant with metastatic deposits of adenocarcinoma in lymph node fine needle aspiration cytology: A chance finding. J Cytol. 2010 Apr; 27(2): 78–80.
24. Agarwal PK, Srivastava AN, Agarwal N. Microfialria in association with neoplasms. A report of six cases. Acta Cytol 1982; 26: 480-90.
CITATION
DOI: 10.17511/jopm.2017.i01.11
How to Cite
Dr. Rita Yadav, Dr. Mala Sagar, Dr. Malti Kumari Maurya, Dr. AA Sonkar, & Dr. Ashutosh Kumar. (1). Microfilaria in fine needle aspiration smears of neoplastic lesions: a case series. Tropical Journal of Pathology and Microbiology, 3(1), 62-66. https://doi.org/10.17511/jopm.2017.i01.11
Section
Case Series
OAI - Open Archives Initiative
