Mycosis fungoides- adnexotropic variant -a rare case report
Keywords:
Adnexotropic, Cutaneous, Lymphoma, Mycosis Fungoides
Abstract
Mycosis fungoides accounts for <1% of non hodgkins lymphomas. It is the commonest cutaneous T cell lymphoma comprising 44% of cutaneous lymphomas. It is clinically characterised by patch, plaque and tumor nodules. Herein we present a case of a female patient of 56 years who presented with multiple papular and nodular lesions of extremities, chest wall and ulcerated nodular lesion of scalp since 6 months.
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References
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Gardner JM, Evans KG, Musiek A, Rook AH, Kim EJ. Update on treatment of cutaneous T-cell lymphoma. Curr Opin Oncol. 2009 Mar;21(2):131-7. doi: 10.1097/CCO.0b013e3283253190.
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Pope E, Weitzman S, Ngan B, Walsh S, Morel K, Williams J, Stein S, Garzon M, Knobler E, Lieber C, Turchan K, Wargon O, Tsuchiya A. Mycosis fungoides in the pediatric population: report from an international Childhood Registry of Cutaneous Lymphoma. J Cutan Med Surg. 2010 Jan-Feb;14(1):1-6.
Massone C, Kodama K, Kerl H, Cerroni L. Histopathologic features of early (patch) lesions of mycosis fungoides: a morphologic study on 745 biopsy specimens from 427 patients. Am J Surg Pathol. 2005 Apr;29(4):550-60.
Murphy GF, Schwarting R (2005) Cutaneous lymphomas and leukemias. In Lever’s histopathology of the skin, 9th edition. Lippincot Williams and Wilkins 927–978.
Barcos M. Mycosis fungoides. Diagnosis and pathogenesis. Am J Clin Pathol. 1993 Apr;99(4):452-8.
van Doorn R, Van Haselen CW, van Voorst Vader PC, Geerts ML, Heule F, de Rie M, Steijlen PM, Dekker SK, van Vloten WA, Willemze R. Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients. Arch Dermatol. 2000 Apr;136(4):504-10.
Kim YH, Hoppe RT. Mycosis fungoides and the Sézary syndrome. Semin Oncol. 1999 Jun;26(3):276-89.
Nagatani T, Matsuzaki T, Iemoto G, Kim S, Baba N, Miyamoto H, Nakajima H. Comparative study of cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma. Clinical, histopathologic, and immunohistochemical analyses. Cancer. 1990 Dec 1;66(11):2380-6.
Zackheim HS, Amin S, Kashani-Sabet M, McMillan A. Prognosis in cutaneous T-cell lymphoma by skin stage: long-term survival in 489 patients. J Am Acad Dermatol. 1999 Mar;40(3):418-25.
Jacobs MA, Kocher W, Murphy GF. Combined folliculotropic/syringotropic cutaneous T-cell lymphoma without epidermal involvement: report of 2cases and pathogenic implications. Hum Pathol. 2003 Nov;34(11):1216-20.
Dalton SR, Chandler WM, Abuzeid M, Hossler EW, Ferringer T, Elston DM, LeBoit PE. Eosinophils in mycosis fungoides: an uncommon finding in the patch and plaque stages. Am J Dermatopathol. 2012 Aug;34(6):586-91. doi: 10.1097/DAD.0b013e31823d921b.
Nickoloff BJ. Light-microscopic assessment of 100 patients with patch/plaque-stage mycosis fungoides. Am J Dermatopathol. 1988 Dec;10(6):469-77.
Gardner JM, Evans KG, Musiek A, Rook AH, Kim EJ. Update on treatment of cutaneous T-cell lymphoma. Curr Opin Oncol. 2009 Mar;21(2):131-7. doi: 10.1097/CCO.0b013e3283253190.
Latkowski JA, Heald PW. Cutaneous T cell lymphomas. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editors. Fitzpatrick's dermatology in general medicine. New York: McGraw-Hill; 2003. p.1537-58.
Pope E, Weitzman S, Ngan B, Walsh S, Morel K, Williams J, Stein S, Garzon M, Knobler E, Lieber C, Turchan K, Wargon O, Tsuchiya A. Mycosis fungoides in the pediatric population: report from an international Childhood Registry of Cutaneous Lymphoma. J Cutan Med Surg. 2010 Jan-Feb;14(1):1-6.
Massone C, Kodama K, Kerl H, Cerroni L. Histopathologic features of early (patch) lesions of mycosis fungoides: a morphologic study on 745 biopsy specimens from 427 patients. Am J Surg Pathol. 2005 Apr;29(4):550-60.
Murphy GF, Schwarting R (2005) Cutaneous lymphomas and leukemias. In Lever’s histopathology of the skin, 9th edition. Lippincot Williams and Wilkins 927–978.
Barcos M. Mycosis fungoides. Diagnosis and pathogenesis. Am J Clin Pathol. 1993 Apr;99(4):452-8.
van Doorn R, Van Haselen CW, van Voorst Vader PC, Geerts ML, Heule F, de Rie M, Steijlen PM, Dekker SK, van Vloten WA, Willemze R. Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients. Arch Dermatol. 2000 Apr;136(4):504-10.
Kim YH, Hoppe RT. Mycosis fungoides and the Sézary syndrome. Semin Oncol. 1999 Jun;26(3):276-89.
Nagatani T, Matsuzaki T, Iemoto G, Kim S, Baba N, Miyamoto H, Nakajima H. Comparative study of cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma. Clinical, histopathologic, and immunohistochemical analyses. Cancer. 1990 Dec 1;66(11):2380-6.
Zackheim HS, Amin S, Kashani-Sabet M, McMillan A. Prognosis in cutaneous T-cell lymphoma by skin stage: long-term survival in 489 patients. J Am Acad Dermatol. 1999 Mar;40(3):418-25.
Jacobs MA, Kocher W, Murphy GF. Combined folliculotropic/syringotropic cutaneous T-cell lymphoma without epidermal involvement: report of 2cases and pathogenic implications. Hum Pathol. 2003 Nov;34(11):1216-20.
Dalton SR, Chandler WM, Abuzeid M, Hossler EW, Ferringer T, Elston DM, LeBoit PE. Eosinophils in mycosis fungoides: an uncommon finding in the patch and plaque stages. Am J Dermatopathol. 2012 Aug;34(6):586-91. doi: 10.1097/DAD.0b013e31823d921b.
Nickoloff BJ. Light-microscopic assessment of 100 patients with patch/plaque-stage mycosis fungoides. Am J Dermatopathol. 1988 Dec;10(6):469-77.
CITATION
DOI: 10.17511/jopm.2015.i01.05
How to Cite
Arasi N, E., Anunayi. J, Divya Goud S, & Neelaveni, N. (1). Mycosis fungoides- adnexotropic variant -a rare case report. Tropical Journal of Pathology and Microbiology, 1(1), 21-24. https://doi.org/10.17511/jopm.2015.i01.05
Section
Case Report
OAI - Open Archives Initiative
