Clinicopathological profile of uterine fibroid at a medical college hospital
Abstract
Introduction: Leiomyomas are usually asymptomatic. Symptoms may be seen depending on their size, location and hormonal effects. It is the most common uterine tumour seen in gynaecological practice. Knowledge of clinical features and histopathological changes are helpful.
Methods: The present cross-sectional study included 109 cases of uterine fibroid. Clinical details and findings of histopathological examination were noted.
Results: Most of the patients belonged to the age group of 50-60 years. Menstrual irregularities were seen in 71.6% of cases. 39.4% suffered from abdominal pain and infertility was seen in 11.9% cases. In 70.6% of cases, proliferative endometrium was found. Secretory endometrium was seen in 13.8% and atrophic in 10.1%. Most of the cases had intramural fibroid (58.7%). It was subserosal in 19.3% cases and submucosal in 4.6%. Hyaline degeneration was seen in 20.2% cases, cystic degeneration in 4.6% and myxoid degeneration in 3.7%. 67.9% of cases did not show any degeneration.
Conclusion: Hyaline degeneration, myxoid degeneration and cystic degeneration are the commonly seen secondary changes. Proper diagnosis and timely management are essential for the management of these tumours.
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