Elevated procalcitonin in a haematological disorder: case report

  • Dr. Raghunath D. Consultant, GEM Hospital and Research Center, Ramanathapuram, Tamil Nadu, India
  • Dr. Shankar Balasubramanian Registrar, GEM Hospital and Research Center, Ramanathapuram, Tamil Nadu, India
  • Dr. Dhivahar G. Consultant, GEM Hospital and Research Center, Ramanathapuram, Tamil Nadu, India
  • Dr. Shivanshu Misra Surgical Gastroenterologist and Advanced Laparoscopic Surgeon, GEM Hospital and Research Center, Ramanathapuram, Tamil Nadu, India
Keywords: Serum procalcitonin, Biochemical marker, Sepsis, Acute myeloid leukemia (AML)

Abstract

Serum procalcitonin (PCT) is a biochemical marker of sepsis being routinely used in critical care setting for rapid diagnosis and early initiation of antimicrobial agents. Serial monitoring of procalcitonin also correlates well with the progression of sepsis. Though procalcitonin has a high specificity for bacterial sepsis, there are conditions associated with elevation of procalcitonin in the absence of sepsis which need to be considered when there are no signs of improvement with treatment in a patient suspected to have sepsis. We present a case of acute myeloid leukemia (AML) with elevated procalcitonin in a patient with no evidence of sepsis or autoimmune disorder. After initiation of chemotherapy, the patient’s general condition improved and there was a dramatic fall in procalcitonin level.

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Published
2020-02-07
How to Cite
D., R., Balasubramanian, S., G., D., & Misra, D. S. (2020). Elevated procalcitonin in a haematological disorder: case report. Pathology Update: Tropical Journal of Pathology and Microbiology, 6(1), 108-111. https://doi.org/10.17511/jopm.2020.i01.18
Section
Case Report