Myoepithelioma of parotid gland – a diagnosis of immunohistochemistry
Keywords:
Myoepithelioma, Salivary Glands, Immunohistochemistry, Histology, Epithelioid
Abstract
Myoepitheliomas are rare benign tumours occurring from any secretory system of the body having myoepithelial cells. In the salivary glands they have an occurrence of 1% with the parotid gland being the most commonly affected gland. The epithelioid variant consists of nests or cords of round to polygonal cells, with centrally located nuclei and a variable amount of eosinophilic cytoplasm. Since this variant is rare and myoepitheliomas can mimic other benign as well as neoplastic conditions, immunohistochemistry is useful for coming to a conclusive diagnosis. We present a case of epithelioid myoepithelioma diagnosed at our institution with the help of immunohistochemistry.
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References
1. Kasamatsu A, Shiiba M, Nakashima D, Shimada K, Higo M, Ishigami T, et al. Epithelioid myoepithelioma of the hard palate. Oral Maxillofac Surg. 2013;17(1):63-66. doi: 10.1007/s10006-012-0324-y. Epub 2012 Apr 18.
2. Barnes L, Eveson JW, Sidransky D, Reichart P, editors. WHO Classification of tumours. Pathology and genetics of head and neck tumours. 3rd Ed, Volume 9, IARC; 2005.
3. Kermani W, Belcadhi M, Ben Ali M, Sriha B, Bouzouita K. Myoepithelioma of the vallecula: a case report. Ear Nose Throat J. 2011;90(7):E9-E11. doi: 10.1177/014556131109000720.
4. Iguchi H, Yamada K, Yamane H, Hashimoto S. Epithelioid myoepithelioma of the accessory parotid gland: pathological and magnetic resonance imaging findings. Case Rep Oncol. 2014;7(2):310-315. doi: 10.1159/000363099.
5. Sheldon W. H. So-called mixed tumours of the salivary glands. Arch Pathol Lab Med. 1943;35:1-20.
6. Seifert G, Brocheriou C, Cardesa A, Eveson JW. WHO International Histological Classification of Tumours. Tentative Histological Classification of Salivary Gland Tumours. Pathol Res Pract. 1990;186(5):555-581. doi: 10.1016/S0344-0338(11)80220-7.
7. Batsakis JG, Kraemer B, Sciubba JJ. The pathology of head and neck tumors: the myoepithelial cell and its participation in salivary gland neoplasia, Part 17. Head Neck Surg. 1983;5(3):222-233. doi: 10.1002/hed.2890050307.
8. Cunha GB, Camurugy TC, Ribeiro TC, Costa NN, Azevedo AC, Vinhaes ES, Andrade NA. Myoepithelioma of the nasal septum: a rare case of extrasalivary gland involvement. Case Rep Otolaryngol. 2017;2017. doi: 10.1155/2017/7057989.7057989.
9. Oktay M, Yaman H, Belada A, Besir FH, Guclu E. Giant myoepithelioma of the soft palate. Case Rep Otolaryngol. 2014;2014:561259. doi: 10.1155/2014/561259. Epub 2014 Mar 3.
10. Kamburoglu HO, Kayikcpoglu AU, Himmetoglu C. A case of myoepithelioma mimicking a parotid cyst. Ear, Nose Throat J. 2015;94(1):37-40.
11. Nayak JV, Molina JT, Smith JC, Branstetter BF 4th, Hunt JL, Snyderman CH. Myoepithelial neoplasia of the submandibular gland: case report and therapeutic considerations. Arch Otolaryngol Head Neck Surg. 2003;129(3):359-62. doi: 10.1001/archotol.129.3.359.
12. Weitzel M, Cohn JE, Spector H. Myoepithelioma of the Parotid Gland: A Case Report with Review of the Literature and Classic Histopathology. Case Rep Otolaryngol. 2017;2017:6036179. doi: 10.1155/2017/6036179. Epub 2017 Aug 16.
2. Barnes L, Eveson JW, Sidransky D, Reichart P, editors. WHO Classification of tumours. Pathology and genetics of head and neck tumours. 3rd Ed, Volume 9, IARC; 2005.
3. Kermani W, Belcadhi M, Ben Ali M, Sriha B, Bouzouita K. Myoepithelioma of the vallecula: a case report. Ear Nose Throat J. 2011;90(7):E9-E11. doi: 10.1177/014556131109000720.
4. Iguchi H, Yamada K, Yamane H, Hashimoto S. Epithelioid myoepithelioma of the accessory parotid gland: pathological and magnetic resonance imaging findings. Case Rep Oncol. 2014;7(2):310-315. doi: 10.1159/000363099.
5. Sheldon W. H. So-called mixed tumours of the salivary glands. Arch Pathol Lab Med. 1943;35:1-20.
6. Seifert G, Brocheriou C, Cardesa A, Eveson JW. WHO International Histological Classification of Tumours. Tentative Histological Classification of Salivary Gland Tumours. Pathol Res Pract. 1990;186(5):555-581. doi: 10.1016/S0344-0338(11)80220-7.
7. Batsakis JG, Kraemer B, Sciubba JJ. The pathology of head and neck tumors: the myoepithelial cell and its participation in salivary gland neoplasia, Part 17. Head Neck Surg. 1983;5(3):222-233. doi: 10.1002/hed.2890050307.
8. Cunha GB, Camurugy TC, Ribeiro TC, Costa NN, Azevedo AC, Vinhaes ES, Andrade NA. Myoepithelioma of the nasal septum: a rare case of extrasalivary gland involvement. Case Rep Otolaryngol. 2017;2017. doi: 10.1155/2017/7057989.7057989.
9. Oktay M, Yaman H, Belada A, Besir FH, Guclu E. Giant myoepithelioma of the soft palate. Case Rep Otolaryngol. 2014;2014:561259. doi: 10.1155/2014/561259. Epub 2014 Mar 3.
10. Kamburoglu HO, Kayikcpoglu AU, Himmetoglu C. A case of myoepithelioma mimicking a parotid cyst. Ear, Nose Throat J. 2015;94(1):37-40.
11. Nayak JV, Molina JT, Smith JC, Branstetter BF 4th, Hunt JL, Snyderman CH. Myoepithelial neoplasia of the submandibular gland: case report and therapeutic considerations. Arch Otolaryngol Head Neck Surg. 2003;129(3):359-62. doi: 10.1001/archotol.129.3.359.
12. Weitzel M, Cohn JE, Spector H. Myoepithelioma of the Parotid Gland: A Case Report with Review of the Literature and Classic Histopathology. Case Rep Otolaryngol. 2017;2017:6036179. doi: 10.1155/2017/6036179. Epub 2017 Aug 16.
CITATION
DOI: 10.17511/jopm.2019.i10.13
Published: 2019-10-31
How to Cite
Sahai, J., Sahu, S., Hoogar, M., & Gaikwad, P. (2019). Myoepithelioma of parotid gland – a diagnosis of immunohistochemistry. Tropical Journal of Pathology and Microbiology, 5(10), 833-837. https://doi.org/10.17511/jopm.2019.i10.13
Section
Case Report
OAI - Open Archives Initiative
