Morphological study of placenta in hypertensive disorders in pregnancy

  • Dr. Prasenjit Kumar Bar Malda Medical College, Malda, West Bengal, India.
  • Dr. Saswata Ghosh Malda Medical College, Malda, West Bengal, India.
  • Dr. Prosenjit Gayen Malda Medical College, Malda, West Bengal, India.
  • Dr Saikat Mandal Malda Medical College, Malda, West Bengal, India.
  • Dr. Anuradha De (Pati) School of Tropical Medicine, Kolkata
  • Aditi Biswas Mollarpur Girls’ High School, Birbhum, West Bengal, India.
Keywords: Hypertensive Disorders, Morphology, Placenta, Pregnancy

Abstract

Introduction: Hypertensive disorders are common complications of pregnancy. Thorough macroscopic and microscopic examination of the placenta provides much insight into the prenatal health of the baby and the mother.

Objectives: 1. To study the morphological changes in the placenta in pregnant mothers. 2. Comparative study of morphological changes in the placenta among hypertensive and normotensive pregnant mothers.

Methods: An Observational Prospective Cohort Study was performed. Detail clinical history taken and placentae were collected from both 40 hypertensive and 40 normotensive mother's delivered in labour room or operation theatre. Both macroscopical and histopathological examination was done. Findings were recorded and analyzed statistically.

Results: The comparison of placental diameter, placental thickness, mean placental weight, placental volume, placental surface area between hypertensive and normotensive group showed statistically significant difference (p value < 0.05). Incidence of placental haematoma, infarction, basement membrane thickening of villi and syncytial knot in hypertensive group was 20%, 27.5%, 50% and 92.5% & in normotensive group was 5%, 10%, 12 % and 60% respectively. All cases in hypertensive group had placental fibrinoid necrosis of villi in comparison to 57.5% cases in normotensive group (p < 0.05). For fibrosis of villi and cytotrophoblatic proliferation p value was < 0.05 which was statistically significant.

Conclusion: Effects of hypertensive disorder in pregnancy reflect in gross and microscopic findings of placenta which may contribute to the further management of mother and baby.

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Morphological study of placenta in hypertensive disorders in pregnancy
CITATION
DOI: 10.17511/jopm.2019.i06.06
Published: 2019-06-30
How to Cite
Dr. Prasenjit Kumar Bar, Dr. Saswata Ghosh, Dr. Prosenjit Gayen, Dr Saikat Mandal, Dr. Anuradha De (Pati), & Aditi Biswas. (2019). Morphological study of placenta in hypertensive disorders in pregnancy. Tropical Journal of Pathology and Microbiology, 5(6), 366-373. https://doi.org/10.17511/jopm.2019.i06.06
Section
Original Article