A study on effect of tobacco on semen quality
Abstract
Introduction: Male infertility has a significant contribution in cases of infertility. Different habits among males i.e. smoking, tobacco chewing and alcohol intake have found adverse influence on sperm count and sperm motility. The mechanisms according to which tobacco affects spermatozoa are poorly understood. Some of the studies focused on the relation between cigarette smoking and the principal semen analysis, variable such as concentration, Morphology and Motility. In this study, we compared the sperm parameters-concentration and motility between tobacco consumers and tobacco non-consumers.
Objectives: To identify the role of smoking and tobacco chewing in decreasing sperm count and motility.
Methods: Total 100 semen samples from the cases of infertility reported at GMERS Medical College & Hospital were taken in this study. The results of tobacco chewers and smokers were studied and compared according to WHO guidelines, to that of tobacco non-consumers.
Results: Out of 100 samples 59 showed decreased sperm count of which 41 men were tobacco consumers. 44 out of 100 samples showed decreased progressive motility, of which 29 men were tobacco consumers.
Conclusion: Tobacco consumption either as smoking or tobacco chewing have a role in deteriorating the sperm quality and therefore in infertility of the male partners.
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References
2. Li Y, Lin H, Li Y, Cao J. Association between socio-psycho-behavioral factors and male semen quality: systematic review and meta-analyses. Fertil Steril. 2011 Jan;95(1):116-23. doi: 10.1016/j.fertnstert.2010.06.031. Epub 2010 Aug 2.[pubmed]
3. WHO laboratory manual for the Examination and processing of human semen. 5th edition. Switzerland: WHO press; 2010.
4. WHO Laboratory manual for the examination of Human semen and Sperm-Cervical mucus interaction. 5thedition. Melbourne: Cambridge University Press;2010
5. Kidd SA, Eskenazi B, Wyrobek AJ. Effects of male age on semen quality and fertility: a review of the literature. FertilSteril. 2001 Feb;75(2):237-48.[pubmed]
6. Zenzes MT. Smoking and reproduction: gene damage to human gametes and embryos. Hum Reprod Update. 2000 Mar-Apr;6(2):122-31.[pubmed]
7. Martelli A, Rousselet E, Dycke C, et al. Cadmium toxicity in animal cells by interference with essential metals. Biochimie. 2006 Nov;88(11):1807-14. Epub 2006 Jun 21. DOI:10.1016/j.biochi.2006.05.013.
8. Chia SE, Ong CN, Chua LH, et al. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. J Androl. 2000 Jan-Feb;21(1):53-7.[pubmed]
9. Elshal MF, El-Sayed IH, Elsaied MA, et al. Sperm head defects and disturbances in spermatozoal chromatin and DNA integrities in idiopathic infertile subjects: association with cigarette smoking. Clin Biochem. 2009 May;42(7-8):589-94. doi: 10.1016/j.clinbiochem.2008.11.012.Epub 2008 Dec 6.[pubmed]
10. Gulaya NM, Margitich VM, Govseeva NM, et al. Phospholipid composition of human sperm and seminal plasma in relation to sperm fertility. Arch Androl. 2001 May-Jun;46(3):169-75.[pubmed]
11. Arabi M, Moshtaghi H. Influence of cigarette smoking on spermatozoa via seminal plasma. Andrologia. 2005 Aug;37(4):119-24. DOI:10.1111/j.1439-0272.2005.00664.x.[pubmed]
12. Kao SH, Chao HT, Chen HW, et al. Increase of oxidative stress in human sperm with lower motility. FertilSteril. 2008 May;89(5):1183-90. Epub 2007 Jul 31.[pubmed]
13. Chia SE, Lim ST, Tay SK, et al. Factors associated with male infertility: a case-control study of 218 infertile and 240 fertile men. BJOG. 2000 Jan;107(1):55-61.[pubmed]
14. Wong WY, Thomas CM, Merkus HM, et al. Cigarette smoking and the risk of male factor subfertility: minor association between cotinine in seminal plasma and semen morphology. FertilSteril. 2000 Nov;74(5):930-5.[pubmed]
15. Künzle R, Mueller MD, Hänggi W, et al. Semen quality of male smokers and nonsmokers in infertile couples. FertilSteril. 2003 Feb;79(2):287-91.[pubmed]
16. Taszarek-H G, Depa-Martynów M, Derwich K, et al. [The influence of cigarette smoking on sperm quality of male smokers and nonsmokers in infertile couples]. PrzeglLek. 2005;62(10):978-81.[pubmed]
17. Hussein A, AlGadaa A, ElFaras M, ElFiky M. Effect of Tobacco Smoking on Semen Quality in Men with Subfertility. Urotoday Int J. 2011;4(1)
18. Kulikauskas V, Blaustein D, Ablin RJ. Cigarette smoking and its possible effects on sperm. FertilSteril. 1985 Oct;44(4):526-8.[pubmed]
19. Said TM, Ranga G, Agarwal A. Relationship between semen quality and tobacco chewing in men undergoing infertility evaluation. FertilSteril. 2005 Sep;84(3):649-53. DOI:10.1016/j.fertnstert.2005.03.052.
20. Coelho C, Júlio C, Silva G, et al. [Tobacco and male infertility: a retrospective study in infertile couples]. Acta Med Port. 2009 Nov-Dec;22(6):753-8. Epub 2010 Jan 10.[pubmed]
21. Collodel G, Capitani S, Iacoponi F, Federico MG, Pascarelli NA, Moretti E. Retrospective assessment of potential negative synergistic effects of varicocele and tobacco use on ultrastructural sperm morphology. Urology. 2009;74(4):794-799.
22. Centers for Disease control and Prevention 2009. Office on Smoking andHealth, National Center for Chronic Disease Prevention and Health Promotion.
23. Choksi T, Patel A, Shrivastav A, Agnihotri AS. Semen analysis: study of hundred samples of semen, in association with different epidemiological parameters, from cases of male infertility. J Res Med Den Sci 2015;3(4):295-7.[pubmed]
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