Cytological study of body fluids for malignancy
Keywords:
Body fluids, Pleural fluid, Peritoneal fluid, CSF, Adenocarcinoma
Abstract
Introduction: The effusion fluid analysis plays an important role in neoplastic conditions. The present study was undertaken to highlight the frequency of malignant cells in various body fluid. Materials and
Methods: This observational study was performed for the period of one and half year. A total of 250 various type of body fluid samples received during the study period in the Department of Pathology, Rajarajeshwari Medical College and Hospital, Bengaluru, Karnataka were studied.
Results: Most of the fluid samples belonged to males (59.20%) and the male to female ratio was 1.45:1. The common age group of specimen received was 40 to 50 years (21.20%). Most of the malignant lesions that is 53.85% and most of the suspicious of malignancy that is 66.67% were belonged to peritoneal fluid.
Conclusions: Pleural fluids were the most common type of fluid received for analysis. Most of the fluid samples belonged to males. The frequency of malignancy in the population studies was 5.20% with adenocarcinoma being the common malignant lesion.
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References
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19. Kol PC, Singh SK, Singh UR. Diagnostic Value of Exfoliative cytology Evaluation of Serous Effusions. International J Sci Res 2016 ; 5(2) : 244-6.
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2. Deshpande AK, Bhaskaran S. Comparative Study of Body Fluid Cytology using Cytospin-II and Ordinary Centrifuge. JEMDS 2015; 4(40):6904-10.
3. Nguyen G.K., Essentials of fluid cytology, Canada: Library and Archives 2009
4. Joshi A, Mahajan N, Karmarkar PJ, Mahore SD. Diagnostic utility of various techniques used in body fluid cytology. IOSR- JDMS 2014; 13(1): 13-8.
5. Poorana PP. Cytological analysis of body fluids in conventional smear and cell block technique study of 120 cases. Int. J Pharm Bio Sci 2015; 6(4),609-15.
6. Sharma M, Sharma A, Khajuria A, Gandhi S. Evaluation of Pathological Body Fluids: An Important Diagnostic Aid India Journal of Basic and Applied Medical Research - Diagnostic research social issue, March 2017;6(2):18-24.
7. Cibas ES. Pleural pericardial and peritoneal fluids. In : Cibas ES and Ducatman BS editors. Cytology: Diagnostic principles and clincal correlate. 3rd ed. Philadelphia : Elsevier : 2009 p. 129-53.
8. Chakrabarti PR, Kiyawat P, Verma A, Agrawal P., Dosi S. Dixit M. Cytological evaluation of serous body fluids: a two year experience in tertiary care centre from the central India Int. J. Cur Res Rev 2015; (17):1-6.
9. Naylor B. Pleural peritoneal and pericardial effusions. In: Bibbo M, Wilbur DC. eds. Comprehensive Cytopathology. 3rd ed., Philadelphia: Elsevier saunders: 2008 p. 515-77.
10. El-Sheikh SA. The Diagnostic Value of Pleural Fluid Cytology in Benign and Malignant Pleural Effusions. Med J Cairo Univ. 2012 ; 80(2): 95-103.
11. Bhanvadia VM, Santwani PM, Vachhani JH. Analysis of diagnostic value of cytological smear method versus cell block method in body fluid cytology: study of 150 cases. Ethiop J Health Sci. 2014 Apr;24(2):125-31.[pubmed]
12. Sulbha VS, Dayananda BS. Cytology of body fluids- an aid to primary diagnosis. Indian J of Pathol Oncol 2015; 2(2):81-3.
13. Mahajan S, Awasthi S, Dutta s. Cytological Diagnosis of Serous Effusions by Using Comparative Approach of Routine Staining and Cytospin Technique Rnn Int. Med. Den Res 2017; 3(4) ; PT 46-51.
14. Shobha SN, Rajashekar YR. Diagnostic approach to pleural effusions. Indian Journal of Pathology and Oncology June 2017;4(2):199-202.
15. Khatib WM, Patel PM. Demde RB, Aher VC. Exfoliative cytology of body fluids: an analysis. Asian Pac J Health Sci, 2016; 3(4): 117-9.
16. Pradhan SB , Pradhan B, Dali S. Cytology of body fluids from different sites: an approach for early diagnosis of malignancy. JNMA J Nepal Med Assoc. 2006 Oct-Dec;45(164):353-6.[pubmed]
17. Ayyagari Sudha, Padmaja Korti, Shailaja Prabhala,, Ashok Kumar Deshpanday. Cytological analysis of body fluids with an emphasis on malignant effusions. Indian journal of pathology and oncology, March 2018;5(1): 106-111
18. Gupta R, Dewan D, Raina R, Gupta M. Exfoliative, cytology of body fluids: a study from provincial hospital of Jammu region, India. Int J Res Med Sci 2016;4:1016-9.
19. Kol PC, Singh SK, Singh UR. Diagnostic Value of Exfoliative cytology Evaluation of Serous Effusions. International J Sci Res 2016 ; 5(2) : 244-6.
20. Jha R, Shrestha HG, Sayami G, et al. Study of effusion cytology in patients with simultaneous malignancy and ascites. Kathmandu Univ Med J (KUMJ). 2006 Oct-Dec;4(4):483-7.[pubmed]
21. Sears D, Hajdu SI. The cytologic diagnosis of malignant neoplasms in pleural and peritoneal effusions. Acta Cytol. 1987 Mar-Apr;31(2):85-97.[pubmed]
22. Wong JW, Pitlik D, Abdul-Karim FW. Cytology of pleural, peritoneal and pericardial fluids in children. A 40-year summary. Acta Cytol. 1997 Mar-Apr;41(2):467-73. DOI:10.1159/000332540.[pubmed]
CITATION
DOI: 10.17511/jopm.2019.i01.08
Published: 2019-01-31
How to Cite
Dr. Husain Saba, Dr. Prakash C.J., Dr. Sharmila P.S, & Dr. Vinitra. K. (2019). Cytological study of body fluids for malignancy. Tropical Journal of Pathology and Microbiology, 5(1), 43-50. https://doi.org/10.17511/jopm.2019.i01.08
Section
Original Article
OAI - Open Archives Initiative
