A study of histopathological spectrum of non-malignant breast lesions

  • Dr. Alpesh M. Maru Department of Pathology, GMERS Medical College, Junagadh, Gujarat, India.
  • Dr. Chiragkumar B. Menapara Department of Pathology, GMERS Medical College, Junagadh, Gujarat, India.
Keywords: Non-malignant, Spectrum, Frequency Distribution

Abstract

Background: Breast Lesions include a variety of Non-malignant and malignant lesions sometimes producing diagnostic difficulty for both Clinicians as well as Pathologists. In certain cases, histopathological examination, particularly microscopy is the only way to reach to the final diagnosis, so our present study is undertaken to know about the Spectrum of variousnon-malignant breast lesions and Frequency of their occurrence.

Materials & Methods: The present study is carried out in the Department of Pathology, GMERS Medical College-Junagadh from September 2015 to August 2018.Excisional and incisional breast biopsies as well as lumpectomy specimens from surgical department have been evaluated both grossly and microscopically for this present study.

Results: Out of 200 cases studied during last 3 years, 155 cases belong to non-malignant (non-neoplastic and benign) lesions while 45 cases belong to malignantlesions (breast cancers). The incidence of non-malignant breast lesions is found to be 77.50 % of all breast lesions. Out of all non-malignant breast lesions, Fibroadenoma is found to be the commonest one (Total 75 cases, 48.39%) followed by Fibrocystic Disease found in 15 cases (9.68%).

Conclusion: Non-malignant breast lesions include a variety of inflammatory lesions, benign tumors and tumor like conditions. Histopathological evaluation becomes necessary for such cases and plays a pivot role in their final diagnosis.

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References

1. Rangabashyam N, Gnanaprakasam D, Krishnaraj B, et al. Spectrum of benign breast lesions in Madras. J R Coll Surg Edinb. 1983 Nov; 28(6):369-73.[pubmed]

2. Guray M, Sahin AA. Benign breast diseases: classification, diagnosis, and management. Oncologist. 2006 May;11(5):435-49.DOI:10.1634/theoncologist.11-5-435.

3. Srivatsava A, Dhar A. Benign breast disease: a neglected entity. Recent Adv Surg2006;10:175-201.

4. Hughes LE, Mansel RE, Webster DJT. The approach to diagnosis and assessment of benign breast lumps benign disorders and diseases of the breast concepts and clinical management, 2ndedition. London: WB Saunders; 2005:35.

5. Kelsey JL, Gammon MD. Epidemiology of breast cancer. Epidemiol Rev. 1990;12:228-40.[pubmed]

6. Cole P, Mark Elwood J, Kaplan SD. Incidence rates and risk factors of benign breast neoplasms. Am J Epidemiol. 1978 Aug;108(2):112-20.[pubmed]

7. Kulkarni Sangeeta et al, Histopathological spectrum of breast lesions with reference touncommon cases. J ObstetGynecol India 2009;59(5): 444-452.

8. Malik R, Bharadwaj VK. Breast lesions in young females--a 20-year study for significance of early recognition. Indian J Pathol Microbiol. 2003 Oct;46(4):559-62.[pubmed]

9. Pudale S et al. A histopathological study of non-malignant breast lesions. Int J Res Med Sci. 2015 Oct; 3(10):2672-2676.

10. Vijayalakshmi M et al. Prevalence of Benign Breast Disease and Risk of Malignancy in Benign Breast Diseases. IOSR Journal of Dental &Medical Sciences 2016;15(8):32-36.

11. Khanna U: Benign Breast Lump. A study of 250 cases. Maharashtra. Med. Jr. 1985;34: 397.

12. Raja GC, Narayan Singh V. Benign Breast Disease in West Indian Population. Brit M J. 1985; 72:17-18.

13. Oluwole SF, Freeman HP. Analysis of benign breast lesions in blacks. Am J Surg. 1979 Jun;137(6):786-9.[pubmed]

14. Haqque et al. Breast Lesions. A clinic-pathological study of 200 cases of Breast lumps. Ind J Surg. 1980; 42:419-429.

15. O'Hara MF, Page DL. Adenomas of the breast and ectopic breast under lactational influences. Hum Pathol. 1985 Jul;16(7):707-12.[pubmed]

16. James K, Bridger J, Anthony PP. Breast tumour of pregnancy ('lactating' adenoma). J Pathol. 1988 Sep;156(1):37-44.DOI:10.1002/path.1711560109.[pubmed]

17. Choudhary B, Khanna V. Cystosarcoma Phyllodes: A Report of Six Cases. Ind J Surg. 1980; 402-407.
A study of histopathological spectrum of non-malignant breast lesions
CITATION
DOI: 10.17511/jopm.2018.i06.04
Published: 2018-10-31
How to Cite
Dr. Alpesh M. Maru, & Dr. Chiragkumar B. Menapara. (2018). A study of histopathological spectrum of non-malignant breast lesions. Tropical Journal of Pathology and Microbiology, 4(6), 442-447. https://doi.org/10.17511/jopm.2018.i06.04
Section
Original Article