Semen analysis in smokers and non-smokers
Abstract
Background: Semen analysis still remains as a simple, cost effective screening test for evaluation of male in fertility clinic, which provides information on quantitative and qualitative aspects of testicular function. Except in cases of azoospermia, semen analysis does not separate patients in to sterile and fertile group.
Objective:The present study was undertaken to perform the quantitative and qualitative Analysis of Semen and to compare the sperm parameters in smokers and non-smokers.
Materials and methods: A total of 150 cases referred to Pathology department for semen analysis in Katuri Medical College &Hospital, from September 2016 to August 2018 were included in the study. The following criteria was used in the selection of the participants.
Results: The overall quality of sperm was significantly decreased in smokers when compared with non-smokers.
Conclusion:Semen parameters like volume, motility, count, morphologically normal spermatozoa were reduced in cigarette smokers when compared to Non-smokers, but only sperm count was found to have a high significant decrease in Smokers (P: <0.01 ) when compared to Non-smokers. In concordance with other researchers, results of present study support that cigarette smoking have a relatively significant effect on semen.
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References
2. Zavos, P.M., Good pasture, J.C.: Clinical use of a seminal collection device: improvements of specific seminal deficiencies through use of a seminal collection device at intercourse versus masturbation. Infertility. 1988; 11(4):289-304.[pubmed]
3. Pound N, Javed MH, Ruberto C, et al. Duration of sexual arousal predicts semen parameters for masturbatory ejaculates. PhysiolBehav. 2002 Aug;76(4-5):685-9.[pubmed]
4. Mortimer D, Menkveld R. Sperm morphology assessment--historical perspectives and current opinions. J Androl. 2001 Mar-Apr;22(2):192-205.[pubmed]
5.Hammond D, Fong GT, Cummings KM, et al. Cigarette yields and human exposure: a comparison of alternative testing regimens. Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1495-501. doi:10.1158/1055-9965.EPI-06-0047.
6. Ochedalski T, Lachowicz-Ochedalska A, Dec W, Czechowski B. [Evaluating the effect of smoking tobacco on some semen parameters in men of reproductive age]. Ginekol Pol. 1994 Feb;65(2):80-6.[pubmed]
7. Künzle R, Mueller MD, Hänggi W, et al. Semen quality of male smokers and nonsmokers in infertile couples. FertilSteril. 2003 Feb;79(2):287-91.[pubmed]
8. Chia SE, Xu B, Ong CN, et al. Effect of cadmium and cigarette smoking on human semen quality. Int J Fertil Menopausal Stud. 1994 Sep-Oct;39(5):292-8.[pubmed]
9. Shaarawy M, Mahmoud KZ. Endocrine profile and semen characteristics in male smokers. FertilSteril. 1982 Aug;38(2):255-7.[pubmed]
10. Saaranen M, Suonio S, Kauhanen O, Saarikoski S. Cigarette smoking and semen quality in men of reproductive age. Andrologia. 1987 Nov-Dec;19(6):670-6.[pubmed]
11. Vine MF, Tse CK, Hu P, Truong KY. Cigarette smoking and semen quality. FertilSteril. 1996 Apr;65(4):835-42.[pubmed]
12. Chia SE, Ong CN, Tsakok FM. Effects of cigarette smoking on human semen quality. Arch Androl. 1994 Nov-Dec;33(3):163-8.[pubmed]
13. Curtis KM, Savitz DA, Arbuckle TE. Effects of cigarette smoking, caffeine consumption, and alcohol intake on fecundability. Am J Epidemiol. 1997 Jul 1;146(1):32-41.[pubmed]
14. Zenzes MT. Smoking and reproduction: gene damage to human gametes and embryos. Hum Reprod Update. 2000 Mar-Apr;6(2):122-31.[pubmed]
15. Vine MF, Tse CK, Hu P, Truong KY. Cigarette smoking and semen quality. FertilSteril. 1996 Apr;65(4):835-42.[pubmed]
16. Zenzes MT, Bielecki R, Reed TE. Detection of benzo(a)pyrene diol epoxide-DNA adducts in sperm of men exposed to cigarette smoke. FertilSteril. 1999 Aug;72(2):330-5.[pubmed]
17. Robert Kunzle, Michael D. Mueller, Willy Hanggi, Martin H. Birkhauser, Heinz Drescher, and Nick A. Bersinger. Semen quality of male smokers and nonsmokers in infertile couples. Fertility and sterility. 2003:79(2):287-291.
18. Vine MF, Tse CK, Hu P, Truong KY. Cigarette smoking and semen quality. FertilSteril. 1996 Apr;65(4):835-42.[pubmed]
19. Vine MF, Hulka BS, Margolin BH, et al. Cotinine concentrations in semen, urine, and blood of smokers and nonsmokers. Am J Public Health. 1993 Sep;83(9):1335-8.[pubmed]
20. Zavos PM, Correa JR, Karagounis CS, et al. An electron microscope study of the axonemal ultrastructure in human spermatozoa from malesmokers and nonsmokers. Fertil Steril. 1998 Mar;69(3):430-4.[pubmed]
21. Zavos PM, Correa JR, Antypas S, Zarmakoupis PN, Zarmakoupis CN. Effects of seminal plasma from cigarette smokers on sperm viability and longevity. FertilSteril1998;69:425–9.
22. Centola GM. Successful treatment of severe oligozoospermia with sperm washing and intrauterine insemination. J Androl. 1997 Jul-Aug;18(4):448-53.[pubmed]
23. Mićić S, Bila S, Ilić V, Sulović V. Treatment of men with oligoasthenozoospermia and asthenozoospermia with kallikrein. Acta Eur Fertil. 1985 Jan-Feb;16(1):51-4.[pubmed]
24. J. Vijayalakshmi, P. Venkatchalam, Solomon F.D. Paul, G. Usha Rani, P. Kumarasamy&Jayam Kannan. Chromosomal Anomalies in Patients with Azoospermia and Oligoasthenoteratozoospermia. Indian Journal of human genetics. 2011;11(2);10-14.
25. Patrick JR, Frank HC, Timothy BH, compilers. In: WHO manual for the standardized investigation, diagnosis and management of the infertile male. Cambridge University Press; 2000.
26. Sepaniak S, Forges T, Fontaine B, et al. Negative impact of cigarette smoking on male fertility: from spermatozoa to the offspring. J GynecolObstet Biol Reprod (Paris). 2004 Sep;33(5):384-90.[pubmed]