Spectrum of Infratentorial Paediatric CNS tumors in a tertiary care hospital
Abstract
Introduction: Due to lack of national wide registry of paediatric brain tumor cases in India, it is difficult to estimate the prevalence and its burden for the nation hence, hospital-based cancer registries will provide the information on the prevalence of tumor cases in a given region.
Objective: The aim of this study is to analyze the incidence of various types of infratentorial paediatric tumors who underwent excision of the tumors from January 2008 to January 2018 in the Department of Neurosurgery, ASRAM, a tertiary care hospital located at Eluru, Andhra Pradesh state in India.
Results: Infratentorial tumors are more common in the paediatric population below the age of 10 years and medulloblastomas being the commonest tumor among them. There is no much difference in the gender distribution in the incidence of Infratentorial tumors in our study.
Conclusion: Our results are similar to other hospital-based data regarding to incidences and histological spectrum of infratentorial tumors. Our study strongly recommends that hospital based registries will provide the magnitude and distribution of cancers in a given region.
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References
2. Nasir S, Jamila B, Khaleeq S. A retrospective study of primary brain tumors in children under 14 years of age at PIMS, Islamabad. Asian Pac J Cancer Prev. 2010;11:1225-27.
3. Wilne SH, Ferris RC, Nathwani A, Kennedy CR. The presenting features of brain tumours: a review of 200 cases. Arch Dis Child. 2006 Jun;91(6):502-6. Epub 2006 Mar 17. doi:10.1136/adc.2005.090266.[pubmed]
4. Louis DN , Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. doi:10.1007/s00401-007-0243-4.[pubmed]
5. Munshi Anusheel. Central nervous system tumors: Spotlight on India. South Asian J Cancer. 2016; 5;146-47.
6. Jalali R, Datta D. Prospective analysis of incidence of central nervous tumors presenting in a tertiary cancer hospital from India. J Neurooncol. 2008 Mar;87(1):111-4. Epub 2007 Nov 15. doi:10.1007/s11060-007-9487-z.[pubmed]
7. Manoharan N, Julka PK, Rath GK. Descriptive epidemiology of primary brain and CNS tumors in Delhi, 2003-2007. Asian Pac J Cancer Prev. 2012;13(2):637-40.[pubmed]
8. Jain A , Sharma MC, Suri V, et al. Spectrum of pediatric brain tumors in India: a multi-institutional study. Neurol India. 2011 Mar-Apr;59(2):208-11. doi: 10.4103/0028-3886.79142.[pubmed]
9. Asirvatham JR , Deepti AN, Chyne R, et al. Pediatric tumors of the central nervous system: a retrospective study of 1,043 cases from a tertiary care center in South India. Childs Nerv Syst. 2011 Aug;27(8):1257-63. doi: 10.1007/s00381-011-1407-z. Epub 2011 Feb 23.[pubmed]
10. Sangita Ramulu Margam, Nitin Maheshwar Gadgil, Ganesh Ramdas Kshirsagar, Vaishali Prashant Gaikwad, Prashant Vijay Kumavat , Chetan Sudhakar Chaudhari. The Histopathological and Epidemiological Study of Pediatric. Annals of Pathology and Laboratory Medicine, 2016; 03:374-381.
11. Shah H, Ubhale B, Shah J. Demographic and histopathologic profile of pediatric brain tumors: A hospital-based study. Pediatric Oncology. 2015; 4:146-48.[pubmed]
12. Qadri S, Hasan M, Akhtar K. Magnitude of neurogenic tumor burden in pediatric population: A tertiary care center study. J Pediatr Neurosci. 2017;12:222-26.[pubmed]
13. Singh A, Singh R, Monalisa, et al. Histological spectrum of central nervous system tumours– A study at a tertiary care centre in Bihar. J. Evolution Med. Dent. Sci. 2017;6:1421-24.
14. Shankar SK. An overview of ontogeny and biology of pediatric brain tumours. In Copybook of abstract, CME in Pediatric Tumour Pathology. Mumbai: Tata Memorial Hospital; 2000.
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