An analysis of skin appendageal tumors: 10 year study
Keywords:
Skin appendageal tumors, Benign, Malignant, Histopathology
Abstract
Introduction: Skin appendageal tumors are wide spectrum of disorders that differentiate towards one or more adnexal structures.
Objective: To determine the prevalence of skin appengeal tumours.
Materials and methods: This is a record based cross sectional study from the Department of pathology, Dr SMCSI Medical College between 1st January 2004 to 1st November 2014 who were diagnosed with skin tumours by histopathology and these cases were reviewed classified and analysed according to the patient's age, gender, and localization.
Results: 166 cases were studied during this study period, males 68 and females 98. Mean age of presentation in this study was 34 years. Tumours with follicular differentiation constituted the maximum, 81 cases (48.8%), followed by eccrine differentiation constituting 22 cases (13.25%): tumours with apocrine differentiation 21cases (12.66%) and sebaceous differentiation 9 cases (5.4%). One case each of sebaceous adenoma and sebaceous carcinoma were the only malignant tumours.
Conclusion: Skin adnexal tumours are relatively uncommon and the incidence of benign skin adnexal tumours are more common compared to the malignant ones.
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References
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13. Saha A, Das NK, Gharami RC, Chowdhury SN, Datta PK. A clinico-histopathological study of appendageal skin tumors, affecting head and neck region in patients attending the dermatology opd of a tertiary care centre in eastern India. Indian J Dermatol 2011;56:33-6.
14. Sharma A, Paricharak DG, Nigam JS, Rewri S, Soni PB, Omhare A, Sekar P. Histopathological study of Skin Adnexal Tumours- Institutional Study in South India. Journal of Skin cancer.2014;1-4.
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22. M. K. Reddy, A. J. Veliath, S. Nagarajan, and A. L. Aurora. A clinicopathological study of adnexal tumours of skin. Indian Journal of Medical Research, vol. 75, no. 6, pp. 882–889, 1982. [PubMed]
23. Sri Gayathri S, EzhilvizhiAlavandar, Ashok Kumar. An Analysis of skin appendageal Tumors in South India. Journal of Evolution of Medical and Dental Sciences.2013;1(6):907 -912.
24. Pujani M, Madaan GB, JairajpuriZS, et al. Adnexal Tumors of Skin: An Experience at a Tertiary Care Center at Delhi. doi: 10.4103/amhsr.amhsr_339_14. [PubMed]
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26. Veraldi S, Schianchi-Veraldi R, Marini D. Hidradenoma papilliferum of the vulva: report of a case characterized by unusual clinicalbehavior. J Dermatol Surg Oncol. 1990 Jul;16(7):674-6.
27. Vang R, Cohen PR. Ectopic hidradenoma papilliferum: a case report and review of the literature. J Am Acad Dermatol. 1999 Jul;41(1):115-8. [PubMed]
2. Stantaylor R, Perone JB, Kaddu S, Kerl H. Appendage Tumors and Hamartomas of the Skin. In: Wolff K, Goldsmith L, Katz S, Gilchrest BA, Paller AS, Leffell DJ, ed. Fitzptrick's Dermatology in General Medicine. 7 th edition. New York: McGraw Hill; 2008. p. 1068-87.
3. Radhikha K, Phaneendra BV, Rukmangadha N, Reddy MK. A study of biopsy confirmed skin adnexal tumors: Experience at a tertiary care teaching hospital. J Clin Sci Res 2013July ;2(3):132-8.
4. Ramirez Claudia C, Berman Brian. Cutaneous Sign and Syndromes Associated with internal Malignancies. SkinMed. 2005: 4(2): 84-90.
5. U Jindal, R Patel. Study Of Adnexal Tumors Of The Skin: A Three Year Study Of 25 Cases. The Internet Journal of Pathology.2012 Volume 13 Number 3.
6. LeBoitP,BurgG,Weedon D Sarasin A. Pathology and genetics of skin tumors. Lyon: IARC Press; 2006.
7. Penneys NS. Immunohistochemistry of adnexal neoplasms. J Cutan Pathol. 1984 Oct;11(5):357-64.
8. Paudyal et al A clinico-histopathological study on skin appendageal tumors J of Pathology of Nepal (2016) Vol.6,885-891.
9. Samaila MO. Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med. 2008 Mar;7(1):6-10.
10. Kamyab-Hesari et al Clinicopathological Study of 1016 Consecutive Adnexal Skin Tumors Acta MedicaIranica, Vol. 51, No. 12 (2013) 879-85
11. Gonzalez L, Di Martino B, Rodriguez M, KnopfelmachlerO, Lourdes Bolla, Recalde J. Clinical and epidemiological study of adnexal tumours at the Dermatology Department of the Medical Sciences Faculty, National University ofAsuncion. Paraguay, 2002-2008. Folia Dermatol Peru2009; 20: 135-9.
12. Kaur K. Gupta K, HemrajaniD, et al. Histopathological Analysis of Skin Adnexal Tumors: A Three Year Study of 110 Cases at A Tertiary Care Center. doi: 10.4103/ijd.IJD_380_16.
13. Saha A, Das NK, Gharami RC, Chowdhury SN, Datta PK. A clinico-histopathological study of appendageal skin tumors, affecting head and neck region in patients attending the dermatology opd of a tertiary care centre in eastern India. Indian J Dermatol 2011;56:33-6.
14. Sharma A, Paricharak DG, Nigam JS, Rewri S, Soni PB, Omhare A, Sekar P. Histopathological study of Skin Adnexal Tumours- Institutional Study in South India. Journal of Skin cancer.2014;1-4.
15. Rajalakshmi V, Selvakumar S, Rajeswari K, et al. Case series of skin adnexal tumours. DOI:10.7860/JCDR/2014/8710.4844
16. El Ochi MR, Boudhas A, AllaouiM, et al. Skin adnexal tumors: Histological study about 96 cases. doi: 10.11604/pamj.2015.20.389.6202. eCollection 2015. [PubMed]
17. Nair PS. A clinicopathologic study of skin appendageal tumors. Indian J Dermatol VenereolLeprol. 2008 Sep-Oct;74(5):550.
18. Ackerman AB . Differentiation of benign from malignant neoplasms by silhouette. Am J Dermatopathol. 1989 Aug;11(4):297-300. [PubMed]
19. Cotton D, Troublesome tumours. 1: Adnexal tumours of the skin. J Clin Pathol. 1991 Jul;44(7):543-8.
20. TirumalaeR , Roopa M. Benign vs. Malignant Skin Adnexal Neoplasms: How Useful are Silhouettes? doi: 10.4103/0019-5154.105282.
21. Vaishnav VP, Dharkar DD. Adnexal tumours of skin. Indian J PatholBacteriol. 1974 Jan;17(1):33-8.
22. M. K. Reddy, A. J. Veliath, S. Nagarajan, and A. L. Aurora. A clinicopathological study of adnexal tumours of skin. Indian Journal of Medical Research, vol. 75, no. 6, pp. 882–889, 1982. [PubMed]
23. Sri Gayathri S, EzhilvizhiAlavandar, Ashok Kumar. An Analysis of skin appendageal Tumors in South India. Journal of Evolution of Medical and Dental Sciences.2013;1(6):907 -912.
24. Pujani M, Madaan GB, JairajpuriZS, et al. Adnexal Tumors of Skin: An Experience at a Tertiary Care Center at Delhi. doi: 10.4103/amhsr.amhsr_339_14. [PubMed]
25. van der Putte SC. Mammary-like glands of the vulva and their disorders. Int J GynecolPathol. 1994 Apr;13(2):150-60. [PubMed]
26. Veraldi S, Schianchi-Veraldi R, Marini D. Hidradenoma papilliferum of the vulva: report of a case characterized by unusual clinicalbehavior. J Dermatol Surg Oncol. 1990 Jul;16(7):674-6.
27. Vang R, Cohen PR. Ectopic hidradenoma papilliferum: a case report and review of the literature. J Am Acad Dermatol. 1999 Jul;41(1):115-8. [PubMed]
CITATION
DOI: 10.17511/jopm.2018.i03.05
Published: 2018-07-31
How to Cite
Dr. Junu Rajan, Dr. Apuca Susan Mathew, & Dr. B Jayalekhmi. (2018). An analysis of skin appendageal tumors: 10 year study. Tropical Journal of Pathology and Microbiology, 4(3), 265-269. https://doi.org/10.17511/jopm.2018.i03.05
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OAI - Open Archives Initiative
