Liver autopsy study – incidental pathological findings

  • Dr. Aniruddha Behera Department of Pathology, VIMSAR, Burla, Sambalpur, Odisha, India.
  • Dr. Alaka Sahu Department of Pathology, VIMSAR, Burla, Sambalpur, Odisha, India.
  • Dr. Salil Kumar Nayak Department of Pathology, VIMSAR, Burla, Sambalpur, Odisha, India.
  • Dr. Kailash Chandra Agrawal Department of Pathology, VIMSAR, Burla, Sambalpur, Odisha, India.
Keywords: Autopsy, Fatty, Liver, Silent


Background: Liver is the site of many diseases, many of which become symptomatic while some are diagnosed only on autopsy. Involvement of liver is secondary to cardiac, metabolic, social problem like alcoholism, drug toxicity, injudicious use of topical applications, herbal remedies and environmental exposures.

Aims and Objectives: In apparently healthy individuals autopsy study sometimes reveals liver diseases. Hence this study aims at finding the frequency and the histopathological appearances in random liver autopsy, so as to evoke public awareness against alcoholism, drug toxicity and potential toxins (perfumes, shampoo, cleaning solvents, pesticides fertilizers,).

Materials and Methods: The present study was carried out in the Department of Pathology & Department of Forensic Medicine and Toxicology, VIMSAR, Burla, Odisha over a period of 2 years. The liver specimens collected from 64 cases were examined grossly as well as microscopically to establish the presence of liver diseases and also to find out the types of liver diseases.

Results: Out of 64 specimens, fatty change, chronic venous congestion, hepatitis, cirrhosis, Steatohepatitis, and drug toxicity cases are reported; fatty change being the predominant finding. Liver diseases predominated in males with male to female ratio of 5:1.

Conclusion: Autopsy examination of liver was very helpful to identify silent liver diseases.


Download data is not yet available.


1. Sotoudehmanesh R, Sotoudeh M, Ali-Asgari A, Abedi-Ardakani B, Tavangar SM, Khakinejad A, Sadeghi Z, Malekzadeh R. Silent liver diseases in autopsies from forensic medicine of Tehran. Arch Iran Med. 2006 Oct;9(4):324-8. [PubMed]

2. Bal MS, Singh SP, Bodal VK, et al. Pathological findings in Liver autopsy. JIAFM, 2004; 26(2); 55-57.

3. Saphir O. Liver 4th ed. Autopsy diagnosis and techniques by Paul B, Hobber, New York. 1958:354-65.

4. Isak K, Markin R. Liver. Anderson’s Pathology;1990:Vol.2.:1787.

5. Alagarsamy J, Muthureddy Y et al. Incidentally discovered diseases – An Autopsy Study of Fifty Cases. International Journal of Science and Research.2014; 3(5):1332.

6. Thamil Selvi R, Selvam V et al. Common Silent Liver Disease In and Around of Salem Population: An Autopsy Study. Journal of Clinical and Diagnostic Research.2012;6(2):207-10.

7. Singal P,Kaur M, D eepika. Incidental Findings in Autopsy Examination of Liver : A Study of 70 Cases .Ann. Int. Med. and Den. Res. 2017;3(3),PT30-PT32.

8. Desmet V, Rosai J. Liver : Rosai and Akerman’s Surgical Pathology. Vol 1.St Louis,USA : Elsevier Mosby; 2004:925-940.

9. Devi Ph. M, Myrthong B G, Meera Th., Nabachandra H. Pathological Findings of Liver in Autopsy Cases A Study at Imphal.J Indian Acad Forensic Med. 2013;35:206.

10. Theise Neil D. Liver and Gall bladder . Robbins and Cotran Pathologic basis of disease;Vol.2. South Asia Edition. Elsevier India; 2014:837-841.
Liver autopsy study – incidental pathological findings
DOI: 10.17511/jopm.2017.i04.05
Published: 2017-12-31
How to Cite
Dr. Aniruddha Behera, Dr. Alaka Sahu, Dr. Salil Kumar Nayak, & Dr. Kailash Chandra Agrawal. (2017). Liver autopsy study – incidental pathological findings. Tropical Journal of Pathology and Microbiology, 3(4), 390-395.
Original Article