@article{Dr. Annu Elizabeth Prakash_Dr. Navya Narayanano_Dr. Siyad Pokkakillath Mohamed_Dr. Rasmi Unnikrishnan_2020, title={The utility of Fine Needle Aspiration Cytology in the Diagnosis of Lymphadenopathy}, volume={6}, url={https://pathology.medresearch.in/index.php/jopm/article/view/496}, DOI={10.17511/jopm.2020.i08.03}, abstractNote={<p>Introduction: The causes of lymphadenopathy may be varied ranging from reactive to neoplastic. Fine Needle Aspiration Cytology(FNAC) is a simple and inexpensive diagnostic tool to sample cells from superficial and accessible sites.</p> <p>Aims: This study was undertaken to assess the utility of FNAC in evaluating lymphadenopathy and to study the cytomorphological spectrum of lymph node lesions in our region.</p> <p>Settings and Design: A cross-sectional study of two years duration, on patients with lymphadenopathy who came to the Pathology Department for FNAC.</p> <p>Methods and materials: Cytology findings of Lymph node lesions were classified into four categories and were compared with histopathology diagnosis as the gold standard.</p> <p>Statistical Analysis: Data was tabulated according to various parameters. Sensitivity, Specificity, PPV, NPV, and Diagnostic accuracy for detecting malignancy were calculated.</p> <p>Results: The age range of patients included in the present study ranged from 9 to – 78 years. The mean age is 48.92 years and the median is 52 years. The cytological diagnosis was classified as reactive in 20 cases (32.7%), inflammatory in 16 cases (26.2%), lymphoma in 3 cases (4.9%), and 22 cases (36.1%) were metastasis from other sites. Following histopathology, the cases were diagnosed to be 19 reactive lymphadenopathies, 14 inflammatory lesions, 5 lymphomas, and 23 metastasis. The most common site of lymphadenopathy was the cervical region.</p> <p>Conclusions: FNAC has high sensitivity and specificity in differentiating benign lesions from malignant ones. The age, clinical findings, and supporting investigations should be taken into account while diagnosing a lesion as benign or malignant.</p&gt;}, number={8}, journal={Tropical Journal of Pathology and Microbiology}, author={Dr. Annu Elizabeth Prakash and Dr. Navya Narayanano and Dr. Siyad Pokkakillath Mohamed and Dr. Rasmi Unnikrishnan}, year={2020}, month={Dec.}, pages={472-480} }